Table 3 Univariable and multivariable Cox regression model for 90-day mortality in entire cohorts

Age, yr

1.07 (1.06, 1.08)

< 0.001

1.03 (1.02, 1.04)

< 0.001

Sex: male (vs female)

2.34 (1.90, 2.88)

< 0.001

1.81 (1.34, 2.43)

< 0.001

Body mass index, kg m⁻²

0.80 (0.78, 0.83)

< 0.001

0.83 (0.80, 0.85)

< 0.001

Insurance type: Medical aid beneficiary program

2.93 (1.95, 4.39)

< 0.001

1.30 (0.85, 1.98)

0.229

 Never married

1

(< 0.001)

1

(0.191)

 Married or living together

1.80 (1.19, 2.73)

0.005

0.60 (0.37, 0.97)

0.038

 Divorced or separated

1.31 (0.59, 2.92)

0.504

0.52 (023, 1.19)

0.119

 Widowed

3.63 (2.16, 6.13)

< 0.001

0.56 (0.31, 1.04)

0.065

 Lower than high school

1

(< 0.001)

1

(0.056)

 More than or equal to high school, lower than college

0.42 (0.33, 0.54)

< 0.001

0.79 (0.61, 1.02)

0.065

 More than or equal to college

0.35 (0.28, 0.45)

< 0.001

0.75 (0.58, 0.97)

0.027

 Office worker

1

(< 0.001)

1

(0.076)

 Licensed job

0.84 (0.46, 1.51)

0.553

0.88 (0.49, 1.60)

0.677

 House work

1.36 (0.91, 2.03)

0.129

1.19 (0.74, 1.91)

0.467

 Self-employed

1.43 (0.88, 2.31)

0.150

0.91 (0.56, 1.49)

0.716

 Student, military, or labourer

1.81 (1.67, 2.80)

0.008

1.07 (0.68, 1.68)

0.778

 Unemployed

6.73 (4.66, 7.91)

< 0.001

1.47 (0.98, 2.21)

0.063

 1

1

(< 0.001)

1

(< 0.001)

 2

7.73 (5.42, 11.03)

< 0.001

5.38 (3.69, 7.91)

< 0.001

 3

54.56 (37.43, 79.53)

< 0.001

21.56 (14.02, 33.16)

< 0.001

  ≥ 4

138.51 (61.52, 311.82)

< 0.001

42.44 (17.89, 100.66)

< 0.001

Hypertension

1.71 (1.39, 2.11)

< 0.001

0.66 (0.52, 0.83)

< 0.001

Diabetes mellitus

2.29 (1.78, 2.95)

< 0.001

0.97 (0.75, 1.27)

0.824

Ischemic heart disease

3.87 (2.91, 5.14)

< 0.001

0.90 (0.66, 1.23)

0.509

Cerebrovascular disease

3.02 (2.17, 4.21)

< 0.001

0.90 (0.64, 1.27)

0.546

Liver disease (fatty liver, hepatitis, liver cirrhosis)

2.56 (1.68, 3.90)

< 0.001

1.81 (1.18, 2.76)

0.006

Dyslipidemia

3.28 (1.85, 5.82)

< 0.001

1.20 (0.67, 2.15)

0.540

Chronic kidney disease

8.95 (4.91, 16.30)

< 0.001

1.89 (1.02, 3.52)

0.045

Cancer

5.27 (4.23, 6.56)

< 0.001

3.32 (2.64, 4.17)

< 0.001

Surgery time, hour

1.01 (1.01, 1.02)

< 0.001

1.01 (1.01, 1.02)

< 0.001

Anesthesia time, hour

1.27 (1.22, 1.32)

< 0.001

Emergency surgery

2.36 (0.33, 16.78)

0.392

1.32 (0.20, 10.28)

0.727

 General surgery

1

(< 0.001)

1

(0.007)

 Thoracic surgery

2.14 (1.53, 2.99)

< 0.001

1.36 (0.97, 1.92)

0.079

 Neuro or spine surgery

1.04 (0.75, 1.43)

0.832

1.99 (1.38, 2.85)

< 0.001

 Orthopedic surgery

0.65 (0.46, 0.93)

0.017

1.41 (0.97, 2.04)

0.074

 Plastic, Ear-nose-throat, Dental, Eye surgery

0.54 (0.38, 0.77)

0.001

1.31 (0.91, 1.88)

0.150

 Gynecologic or Urologic surgery

0.67 (0.50, 0.90)

0.008

1.04 (0.77, 1.42)

0.785

 2011–2012

1

(0.238)

1

(0.076)

 2013–2014

0.95 (0.74, 1.21)

0.672

0.94 (0.73, 1.21)

0.622

 2015–2016

0.82 (0.65, 1.04)

0.099

0.75 (0.58, 0.97)

0.029

Intraoperative qualitative neuromuscular monitoring

0.05 (0.00, 1.19)

0.064

0.00 (0.00-)

0.893

Intraoperative Rocuronium dosage, per 1 mg kg⁻¹

1.54 (1.39, 1.70)

< 0.001

1.00 (0.97, 1.03)

0.772

Reversal by Sugammadex (vs neostigmine)

0.95 (0.64, 1.42)

0.806

0.62 (0.39, 0.96)

0.036