Variables | Before PS matching (n = 65,702) |  | After PS matching (n = 14,179) |  | ||
---|---|---|---|---|---|---|
Sugammadex | Neostigmine | ASD | Sugammadex | Neostigmine | ASD | |
n = 4578 | n = 61,124 | n = 3906 | n = 10,273 | |||
Age, yr | 57.7 (14.3) | 51.8 (15.7) | 0.41 | 57.2 (14.5) | 55.1 (14.9) | 0.10 |
Sex: male | 2738 (59.8) | 26,517 (43.4) | 0.34 | 2269 (58.1) | 5045 (49.1) | 0.14 |
Body mass index, kg m−2 | 24.2 (3.5) | 24.0 (3.4) | 0.06 | 24.1 (3.5) | 24.0 (3.4) | 0.01 |
Insurance type |  |  | 0.03 |  |  | < 0.01 |
 National health insurance program | 4488 (98.0) | 59,706 (97.7) |  | 3822 (97.8) | 10,045 (97.8) |  |
 Medical aid beneficiary program | 90 (2.0) | 1418 (2.3) |  | 84 (2.2) | 228 (2.2) |  |
Marital status | Â | Â | 0.14 | Â | Â | 0.04 |
 Never married | 268 (5.9) | 6892 (11.3) |  | 230 (5.9) | 784 (7.6) |  |
 Married or living together | 3965 (86.6) | 49,956 (81.7) |  | 3379 (86.5) | 8722 (84.9) |  |
 Divorced or separated | 119 (2.6) | 1698 (2.8) |  | 104 (2.7) | 268 (2.6) |  |
 Widowed | 226 (4.9) | 2578 (4.2) |  | 193 (4.9) | 499 (4.9) |  |
Highest educational attainment | Â | Â | 0.07 | Â | Â | 0.03 |
 Lower than high school | 1066 (23.3) | 13,464 (22.0) |  | 903 (23.1) | 2219 (21.6) |  |
 More than or equal to high school, lower than college | 1434 (31.3) | 21,193 (34.7) |  | 1235 (31.6) | 3340 (32.5) |  |
 More than or equal to college | 2078 (45.4) | 26,467 (43.3) |  | 1768 (45.3) | 4714 (45.9) |  |
Occupation | Â | Â | 0.19 | Â | Â | 0.09 |
 Office worker | 943 (20.6) | 10,838 (17.7) |  | 804 (20.6) | 1988 (19.4) |  |
 Licensed job | 448 (9.8) | 6188 (10.1) |  | 378 (9.7) | 1046 (10.2) |  |
 House work | 1099 (24.0) | 19,753 (32.3) |  | 962 (24.6) | 2996 (29.2) |  |
 Self-employed | 668 (14.6) | 7114 (11.6) |  | 550 (14.1) | 1325 (12.9) |  |
 Student, military, or laborer | 454 (9.9) | 8954 (14.6) |  | 384 (9.8) | 1150 (11.2) |  |
 Unemployed | 966 (21.1) | 8277 (13.5) |  | 828 (21.2) | 1768 (17.2) |  |
Preoperative comorbidities | ||||||
 ASA physical status |  |  | 0.20 |  |  | 0.07 |
 1 | 1891 (41.3) | 32,349 (52.9) |  | 1632 (41.8) | 4814 (46.9) |  |
 2 | 2489 (54.4) | 26,722 (43.7) |  | 2103 (53.8) | 5044 (49.1) |  |
 3 | 196 (4.3) | 2001 (3.3) |  | 169 (4.3) | 410 (4.0) |  |
  ≥ 4 | 2 (0.0) | 52 (0.1) |  | 2 (0.1) | 5 (0.0) |  |
Hypertension | 1299 (28.4) | 13,402 (21.9) | 0.14 | 1099 (28.1) | 2519 (24.5) | 007 |
Diabetes mellitus | 567 (12.4) | 5611 (9.2) | 0.09 | 482 (12.3) | 1120 (10.9) | 0.02 |
Ischemic heart disease | 262 (5.7) | 2426 (4.0) | 0.08 | 229 (5.9) | 531 (5.2) | 0.03 |
Cerebrovascular disease | 205 (4.5) | 2130 (3.5) | 0.05 | 182 (4.7) | 418 (4.1) | 0.04 |
Liver disease (fatty liver, hepatitis, liver cirrhosis) | 168 (3.7) | 1405 (2.3) | 0.07 | 142 (3.6) | 310 (3.0) | < 0.01 |
Dyslipidemia | 35 (0.8) | 596 (1.0) | 0.02 | 32 (0.8) | 90 (0.9) | < 0.01 |
Chronic kidney disease | 14 (0.3) | 204 (0.3) | < 0.01 | 14 (0.4) | 51 (0.5) | 0.01 |
Cancer | 2695 (58.9) | 18,651 (30.5) | 0.58 | 2242 (57.4) | 5080 (49.5) | < 0.01 |
Operative Characteristics | ||||||
 Surgery time, min | 150.7 (95.1) | 111.8 (145.6) | 0.39 | 148.6 (99.4) | 131.4 (102.2) | 0.05 |
 Anesthesia time, min | 190.8 (104.8) | 150.7 (95.1) | 0.38 | 188.3 (105.4) | 169.6 (109.0) | 0.04 |
 Emergency surgery | 3 (0.1) | 69 (0.1) | 0.02 | 2 (0.1) | 8 (0.1) | 0.01 |
Type of non-cardiac surgery | Â | Â | 1.23 | Â | Â | 0.08 |
 General surgery | 3185 (69.6) | 20,347 (33.3) |  | 2777 (71.1) | 5889 (57.3) |  |
 Thoracic surgery | 40 (0.9) | 2974 (4.9) |  | 40 (1.0) | 214 (2.1) |  |
 Neuro or spine surgery | 81 (1.8) | 6552 (10.7) |  | 81 (2.1) | 461 (4.5) |  |
 Orthopedic surgery | 52 (1.1) | 8654 (14.2) |  | 52 (1.3) | 440 (4.3) |  |
 Plastic, ENT, Dental, Eye surgery | 102 (2.2) | 10,458 (17.1) |  | 128 (3.0) | 639 (6.2) |  |
 Gynecologic or Urologic surgery | 1128 (24.5) | 12,139 (19.9) |  | 838 (21.5) | 2630 (25.6) |  |
Intraoperative rocuronium dosage, mg | Â | Â | 1.26 | Â | Â | 0.02 |
 <  50 | 3 (0.1) | 130 (0.2) |  | 3 (0.1) | 11 (0.1) |  |
 50–100 | 1082 (23.6) | 47,049 (77.0) |  | 1080 (27.6) | 5145 (50.1) |  |
 >  100 | 3493 (76.3) | 13,945 (22.8) |  | 2823 (72.3) | 5117 (49.8) |  |
Intraoperative qualitative neuromuscular monitoring | 78 (1.7) | 1.199 (2.0) | 0.02 | 57 (1.5) | 128 (1.2) | 0.01 |
Year of surgery | Â | Â | 1.83 | Â | Â | 0.09 |
 2011–2012 | 0 (0.0) | 22,198 (36.3) |  | 0 (0.0) | 776 (7.6) |  |
 2013–2014 | 475 (10.4) | 18,215 (29.8) |  | 475 (12.2) | 2156 (21.0) |  |
 2015–2016 | 4103 (89.6) | 20,711 (33.9) |  | 3431 (87.8) | 7341 (71.5) |  |