Skip to main content

Table 1 Comparison between sugammadex group and neostigmine group before and after propensity score matching

From: Association of neuromuscular reversal by sugammadex and neostigmine with 90-day mortality after non-cardiac surgery

Variables

Before PS matching (n = 65,702)

 

After PS matching (n = 14,179)

 

Sugammadex

Neostigmine

ASD

Sugammadex

Neostigmine

ASD

n = 4578

n = 61,124

n = 3906

n = 10,273

Age, yr

57.7 (14.3)

51.8 (15.7)

0.41

57.2 (14.5)

55.1 (14.9)

0.10

Sex: male

2738 (59.8)

26,517 (43.4)

0.34

2269 (58.1)

5045 (49.1)

0.14

Body mass index, kg m−2

24.2 (3.5)

24.0 (3.4)

0.06

24.1 (3.5)

24.0 (3.4)

0.01

Insurance type

  

0.03

  

< 0.01

 National health insurance program

4488 (98.0)

59,706 (97.7)

 

3822 (97.8)

10,045 (97.8)

 

 Medical aid beneficiary program

90 (2.0)

1418 (2.3)

 

84 (2.2)

228 (2.2)

 

Marital status

  

0.14

  

0.04

 Never married

268 (5.9)

6892 (11.3)

 

230 (5.9)

784 (7.6)

 

 Married or living together

3965 (86.6)

49,956 (81.7)

 

3379 (86.5)

8722 (84.9)

 

 Divorced or separated

119 (2.6)

1698 (2.8)

 

104 (2.7)

268 (2.6)

 

 Widowed

226 (4.9)

2578 (4.2)

 

193 (4.9)

499 (4.9)

 

Highest educational attainment

  

0.07

  

0.03

 Lower than high school

1066 (23.3)

13,464 (22.0)

 

903 (23.1)

2219 (21.6)

 

 More than or equal to high school, lower than college

1434 (31.3)

21,193 (34.7)

 

1235 (31.6)

3340 (32.5)

 

 More than or equal to college

2078 (45.4)

26,467 (43.3)

 

1768 (45.3)

4714 (45.9)

 

Occupation

  

0.19

  

0.09

 Office worker

943 (20.6)

10,838 (17.7)

 

804 (20.6)

1988 (19.4)

 

 Licensed job

448 (9.8)

6188 (10.1)

 

378 (9.7)

1046 (10.2)

 

 House work

1099 (24.0)

19,753 (32.3)

 

962 (24.6)

2996 (29.2)

 

 Self-employed

668 (14.6)

7114 (11.6)

 

550 (14.1)

1325 (12.9)

 

 Student, military, or laborer

454 (9.9)

8954 (14.6)

 

384 (9.8)

1150 (11.2)

 

 Unemployed

966 (21.1)

8277 (13.5)

 

828 (21.2)

1768 (17.2)

 

Preoperative comorbidities

 ASA physical status

  

0.20

  

0.07

 1

1891 (41.3)

32,349 (52.9)

 

1632 (41.8)

4814 (46.9)

 

 2

2489 (54.4)

26,722 (43.7)

 

2103 (53.8)

5044 (49.1)

 

 3

196 (4.3)

2001 (3.3)

 

169 (4.3)

410 (4.0)

 

  ≥ 4

2 (0.0)

52 (0.1)

 

2 (0.1)

5 (0.0)

 

Hypertension

1299 (28.4)

13,402 (21.9)

0.14

1099 (28.1)

2519 (24.5)

007

Diabetes mellitus

567 (12.4)

5611 (9.2)

0.09

482 (12.3)

1120 (10.9)

0.02

Ischemic heart disease

262 (5.7)

2426 (4.0)

0.08

229 (5.9)

531 (5.2)

0.03

Cerebrovascular disease

205 (4.5)

2130 (3.5)

0.05

182 (4.7)

418 (4.1)

0.04

Liver disease (fatty liver, hepatitis, liver cirrhosis)

168 (3.7)

1405 (2.3)

0.07

142 (3.6)

310 (3.0)

< 0.01

Dyslipidemia

35 (0.8)

596 (1.0)

0.02

32 (0.8)

90 (0.9)

< 0.01

Chronic kidney disease

14 (0.3)

204 (0.3)

< 0.01

14 (0.4)

51 (0.5)

0.01

Cancer

2695 (58.9)

18,651 (30.5)

0.58

2242 (57.4)

5080 (49.5)

< 0.01

Operative Characteristics

 Surgery time, min

150.7 (95.1)

111.8 (145.6)

0.39

148.6 (99.4)

131.4 (102.2)

0.05

 Anesthesia time, min

190.8 (104.8)

150.7 (95.1)

0.38

188.3 (105.4)

169.6 (109.0)

0.04

 Emergency surgery

3 (0.1)

69 (0.1)

0.02

2 (0.1)

8 (0.1)

0.01

Type of non-cardiac surgery

  

1.23

  

0.08

 General surgery

3185 (69.6)

20,347 (33.3)

 

2777 (71.1)

5889 (57.3)

 

 Thoracic surgery

40 (0.9)

2974 (4.9)

 

40 (1.0)

214 (2.1)

 

 Neuro or spine surgery

81 (1.8)

6552 (10.7)

 

81 (2.1)

461 (4.5)

 

 Orthopedic surgery

52 (1.1)

8654 (14.2)

 

52 (1.3)

440 (4.3)

 

 Plastic, ENT, Dental, Eye surgery

102 (2.2)

10,458 (17.1)

 

128 (3.0)

639 (6.2)

 

 Gynecologic or Urologic surgery

1128 (24.5)

12,139 (19.9)

 

838 (21.5)

2630 (25.6)

 

Intraoperative rocuronium dosage, mg

  

1.26

  

0.02

 <  50

3 (0.1)

130 (0.2)

 

3 (0.1)

11 (0.1)

 

 50–100

1082 (23.6)

47,049 (77.0)

 

1080 (27.6)

5145 (50.1)

 

 >  100

3493 (76.3)

13,945 (22.8)

 

2823 (72.3)

5117 (49.8)

 

Intraoperative qualitative neuromuscular monitoring

78 (1.7)

1.199 (2.0)

0.02

57 (1.5)

128 (1.2)

0.01

Year of surgery

  

1.83

  

0.09

 2011–2012

0 (0.0)

22,198 (36.3)

 

0 (0.0)

776 (7.6)

 

 2013–2014

475 (10.4)

18,215 (29.8)

 

475 (12.2)

2156 (21.0)

 

 2015–2016

4103 (89.6)

20,711 (33.9)

 

3431 (87.8)

7341 (71.5)

 
  1. Presented as number (percentage) or mean (standard deviation)
  2. PS propensity score; ASD Absolute value of standardized mean difference; ASA American Society of Anesthesiologists; TOF train-of-four