Fig. 3
Exogenous H2S reverses surgery-induced oxidative stress, microglial activation, and cell apoptosis in the hippocampus, which is similar to L-NAME. a The oxidative product MDA and antioxidant enzyme SOD were measured in hippocampal tissue. b The microglial marker IBA-1 (brown) was detected in the hippocampal CA1 and CA3 regions on Day 1 post-surgery using IHC staining. Scale bars: × 100, 200 μm; × 200, 100 μm. c Neuronal apoptosis in the hippocampal CA1 and CA3 regions was detected on Day 1 post-surgery using TUNEL staining. Scale bars: × 100, 200 μm; × 200, 100 μm. * P < 0.05, compared with the sham group; # P < 0.05, compared with the surgery group