Fig. 2
Exogenous H2S reverses surgery-induced neuroinflammation on Days 1 and 4 post-surgery but not on Day 8 post-surgery, which may be related to reduced hippocampal NO and iNOS. a and b Concentrations of IL-1β and TNF-α in the hippocampus were detected by ELISA on Days 1, 4, and 8 post-surgery. c Concentrations of hippocampal NO were measured using the nitrate reductase method at 24 h post-surgery. d Hippocampal iNOS was detected by WB at 24 h post-surgery. IL-1β, interleukin-1β; TNF-α, tumor necrosis factor α; NO, nitric oxide; iNOS, inducible nitric oxide synthase. * P < 0.05, compared with the sham group; ** P < 0.01, compared with the sham group; # P < 0.05, compared with the surgery group; ## P < 0.01, compared with the surgery group