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Table 1 Data for Patients Overall and Matched Patients after Propensity Scoring

From: Anesthetics and long-term survival after cancer surgery—total intravenous versus volatile anesthesia: a retrospective study

 

Overall Patients

Matched Patients

Variables

TIVA (n = 903)

VIA (n = 1304)

ASD

P

TIVA (n = 729)

VIA (n = 729)

ASD

P

Age, yr

58.0 [49.0;67.0]

57.0 [48.0;67.0]

0.098

0.018

58.0 [49.0;67.0]

57.0 [48.0;67.0]

0.003

0.861

Sex

  

0.233

< 0.001

  

0.019

0.753

 Female

404 (44.7%)

734 (56.3%)

  

337 (46.2%)

344 (47.2%)

  

 Male

499 (55.3%)

570 (43.7%)

  

392 (53.8%)

385 (52.8%)

  

Height, cm

161.0 [154.0;166.0]

159.0 [154.0;165.0]

0.118

0.007

161.0 [154.0;166.0]

161.0 [155.0;166.0]

0.015

0.610

Weight, kg

60.0 [54.0;67.0]

60.0 [54.0;67.0]

0.002

0.368

60.0 [54.0;67.0]

60.0 [53.0;67.0]

0.023

0.527

BMI, kg m−2

23.6 [21.8;25.8]

23.8 [21.8;26.1]

0.062

0.210

23.6 [21.7;25.8]

23.5 [21.5;25.8]

0.039

0.577

ASA class

  

0.098

0.067

  

0.053

0.605

 I

399 (44.2%)

633 (48.5%)

  

311 (42.7%)

310 (42.5%)

  

 II

503 (55.7%)

671 (51.5%)

  

417 (57.2%)

419 (57.5%)

  

 III

1 (0.1%)

0 (0.0%)

  

1 (0.1%)

0 (0.0%)

  

Hypertension

  

0.008

0.894

  

< 0.001

1.000

 Yes

233 (25.8%)

341 (26.2%)

  

188 (25.8%)

188 (25.8%)

  

 No

670 (74.2%)

963 (73.8%)

  

541 (74.2%)

541 (74.2%)

  

DM

  

0.057

0.204

  

0.032

0.593

 Yes

121 (13.4%)

150 (11.5%)

  

95 (13.0%)

103 (14.1%)

  

 No

782 (86.6%)

1154 (88.5%)

  

634 (87.0%)

626 (85.9%)

  

Anesthesia time, min

230.0 [185.0;285.0]

210.0 [170.0;260.0]

0.166

< 0.001

215.0 [180.0;260.0]

220.0 [180.0;265.0]

0.017

0.696

Operation time, min

190.0 [150.0;240.0]

175.0 [135.0;220.0]

0.146

< 0.001

180.0 [149.0;220.0]

180.0 [149.0;225.0]

0.012

0.787

Remifentanil infusion

   

< 0.001

   

< 0.001

 Yes

902 (99.9%)

701 (53.8%)

  

728 (99.9%)

395 (54.2%)

  

 No

1 (0.1%)

603 (46.2%)

  

1 (0.1%)

334 (45.8%)

  

Gas type

   

< 0.001

   

< 0.001

 Des

0 (0.0%)

345 (26.5%)

  

0 (0.0%)

193 (26.5%)

  

 Iso

0 (0.0%)

31 (2.4%)

  

0 (0.0%)

25 (3.5%)

  

 Sevo

0 (0.0%)

927 (71.1%)

  

0 (0.0%)

511 (70%)

  

Nitrous oxide

   

< 0.001

   

< 0.001

 Yes

1 (0.1%)

550 (42.2%)

  

1 (0.1%)

302 (41.4%)

  

 No

902 (99.9%)

754 (57.8%)

  

728 (99.9%)

427 (58.6%)

  

Metastasis at surgery

  

0.006

0.947

  

0.014

0.855

 Yes

68 (7.5%)

96 (7.4%)

  

64 (8.8%)

67 (9.2%)

  

 No

835 (92.5%)

1208 (92.6%)

  

665 (91.2%)

662 (90.8%)

  

Transfusion

  

0.056

0.252

  

0.038

0.626

 Yes

19 (2.1%)

39 (3.0%)

  

10 (1.4%)

7 (1.0%)

  

 No

884 (97.9%)

1265 (97.0%)

  

719 (98.6%)

722 (99.0%)

  

Hospital stay, day

13.0 [11.0;18.0]

13.0 [10.0;18.0]

0.014

0.238

13.0 [11.0;18.0]

13.0 [10.0;18.0]

0.023

0.355

Survival, month

60.0 [44.0;60.0]

60.0 [45.0;60.0]

 

0.945

60.0 [40.0;60.0]

60.0 [47.0;60.0]

 

0.523

5 years survival

   

0.291

   

0.262

 Yes

829 (91.8%)

1214 (93.1%)

  

660 (90.5%)

673 (92.3%)

  

 No

74 (8.2%)

90 (6.9%)

  

69 (9.5%)

56 (7.7%)

  

Cancer type

   

< 0.001

   

1.000

 Breast

154 (17.1%)

475 (36.4%)

  

154 (21.1%)

154 (21.1%)

  

 Colon

362 (40.1%)

188 (14.4%)

  

188 (25.8%)

188 (25.8%)

  

 Liver

37 (4.1%)

90 (6.9%)

  

37 (5.1%)

37 (5.1%)

  

 Lung

44 (4.9%)

103 (7.9%)

  

44 (6.0%)

44 (6.0%)

  

 Stomach

306 (33.9%)

448 (34.4%)

  

306 (42.0%)

306 (42.0%)

  
  1. Number (%): chi-square test, median [interquartile range]: Mann–Whitney U test
  2. ASD Absolute standardized mean difference, BMI Body mass index, ASA American Society of Anesthesiologists, TIVA Total intravenous anesthesia, VIA Volatile inhalational anesthesia, DM Diabetes mellitus, Des Desflurane, Iso Isoflurane, Sevo Sevoflurane