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Table 3 Changes in T cells After Surgery

From: Effect of low dose naloxone on the immune system function of a patient undergoing video-assisted thoracoscopic resection of lung cancer with sufentanil controlled analgesia — a randomized controlled trial

 

Naloxone(n = 35)

Non-naloxone(n = 34)

P Value

CD3+T cells(%)

Before surgery

56.94 ± 9.01

56.95 ± 8.98

0.997

24 h after operation

46.22 ± 12.67###

41.48 ± 9.99###

0.089

48 h after operation

56.17 ± 8.96

53.36 ± 10.58

0.237

CD4+T cells(%)

Before surgery

33.49 ± 6.92

32.61 ± 5.52

0.560

24 h after operation

25.39 ± 8.55###

21.20 ± 7.81###

0.037

48 h after operation

32.70 ± 6.39

28.91 ± 6.11#

0.014

CD8+T cells(%)

Before surgery

23.45 ± 4.37

24.34 ± 5.09

0.437

24 h after operation

20.83 ± 7.02#

20.28 ± 6.54##

0.734

48 h after operation

23.47 ± 4.10

24.57 ± 6.21

0.391

CD4+/CD8+ T cell ratio

Before surgery

1.49 ± 0.36

1.39 ± 0.30

0.226

24 h after operation

1.32 ± 0.51

1.15 ± 0.52#

0.163

48 h after operation

1.41 ± 0.27

1.21 ± 0.29

0.003

  1. CD Clusters of Differentiation
  2. #P<0.05 versus “before surgery” for each group. ##P<0.01 versus “before surgery” for each group, ###P<0.001 versus “before surgery” for each group