From: Effect of low dose naloxone on the immune system function of a patient undergoing video-assisted thoracoscopic resection of lung cancer with sufentanil controlled analgesia — a randomized controlled trial
Naloxone(n = 35)
Non-naloxone (n = 34)
P Value
NK cells(%)
Before surgery
16.14 ± 5.75
16.63 ± 6.40
0.519
24 h after operation
14.13 ± 6.28
14.53 ± 5.85
0.918
48 h after operation
15.97 ± 5.44
13.06 ± 5.47#
0.030