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Table 1 Infection related characteristics of patients and volunteers

From: Neutrophil extracellular trap formation and nuclease activity in septic patients

Variable

Healthy volunteers (n = 27)

Patients with sepsis (n = 18)

p-value

Mean age, years

33 ± 14

49 ± 17

< 0.0001

Females / males, N (%)

20 (74) / 7 (26)

2 (11) / 16 (89)

< 0.0001

Leukocyte blood concentration (103 μl− 1)

6 ± 1

18 ± 15

0.002

Neutrophil blood concentration (103 μl-1)

3 ± 0.5

17 ± 7

≤0.0001

Immature neutrophils (% of all neutrophils)

n/a

10 ± 12

 

C-reactive protein serum concentration (mg l− 1)

≤0.5 ± 0

22 ± 13

≤0.0001

Procalcitonin serum concentration (ng ml− 1)

n/a

56 ± 96

 

SAPS II

n/a

34 ± 10

 

SOFA

n/a

14 ± 2

 

30-day survival (%)

100

56

 

Gram-positive sepsis N (%)

n/a

6 (33)

 

Gram-negative sepsis N (%)

n/a

5 (28)

 

Mixed bacterial sepsis N (%)

n/a

3 (17)

 

Viral sepsis N (%)

n/a

0

 

Mycotic sepsis N (%)

n/a

2 (11)

 

Sepsis without microbial detection N (%)

n/a

2 (11)

 

Source of infection

1) Pneumonia, N

n/a

8

 

2) Acute respiratory distress syndrome (ARDS) subsequent to prior Pneumonia, but only microbial detection in blood, N

n/a

4

 

3) Urinary tract infection, N

n/a

1

 

4) Abdominal infection

n/a

2

 

5) Thoracic infection

n/a

1

 

6) No focus detected

n/a

2

 
  1. Data from 27 healthy volunteers and 18 septic patients. Data are presented as numbers, percentages, or means ± standard deviation.
  2. p-values relate to Student’s t-test for unpaired samples, where applicable.