t0 | t1 | t2 | t3 | |
---|---|---|---|---|
MAP (mmHg) | ||||
All | 91 [83–102] | 79 [72–86]* | 80 [73–91]* | 82 [73–92]* |
No complications | 93 [82–102] | 83 [73–90] | 84 [77–95] | 84 [74–92] |
Complications | 90 [87–102] | 77 [68–85]* | 75 [71–87]* | 78 [72–91] |
Heart Rate (bpm) | ||||
All | 68 [60–75] | 85 [79–91]* | 87 [80–90]* | 86 [80–90]* |
No complications | 68 [57–77] | 86 [80–90]* | 86 [80–90]* | 86 [79–90]* |
Complications | 70 [61–74] | 86 [80–93]* | 87 [79–90]* | 87 [80–90]* |
CVP (mmHg) | ||||
All | NA | 10 [7–12] | 9 [7–12] | 8 [7–11] |
No complications | NA | 9 [7–12] | 8 [7–12] | 8 [7–11] |
Complications | NA | 10 [8–13] | 10 [8–12] | 9 [7–12] |
Hb (g/dL) | ||||
All | 14.1 [13.2–15.3] | 11.5 [10.3–12.9]* | 12.5 [11.5–13.6]* | 12.4 [11.2–13.5]* |
No complications | 14.1 [13.2–15.6] | 12 [10.5–13.1]* | 12.6 [11.6–13.5] | 12.5 [11.1–13.6]* |
Complications | 14.4 [13.2–15] | 11.1 [10.2–11.8]* | 11.7 [10.6–13.2] | 12 [10.4–12.5] |
Lactate (mmol/l) | ||||
All | 1.4 [1.1–1.9] | 2.3 [1.5–3.3]* | 2.0 [1.4–2.9]* | 1.9 [1.6–2.8]* |
No complications | 1.5 [1.2–2] | 2.0 [1.3–2.6] | 1.8 [1.3–2.7] | 1.9 [1.4–2.6]* |
Complications | 1.3 [1.0–1.6] | 2.0 [1.4–4.1] | 1.8 [1.4–3.5] | 1.9 [1.4–3.2] |
SvO2 (%) | ||||
All | NA | 72 [66–77] | 70 [63–75] | 71 [64–76] |
No complications | NA | 71 [67–75] | 71 [65–75] | 70 [63–76] |
Complications | NA | 74 [63–81] | 69 [60–76] | 72 [65–81] |
CI (L/min/m2) (n) | ||||
All | NA | 2.1 [1.7–2.7] (90) | 1.9 [1.5–2.3] (87) | 2.2 [1.9–2.5] (66) |
No complications | NA | 2.1 [1.8–2.4] (51) | 1.9 [1.6–2.4] (49) | 2.1 [1.8–2.5] (34) |
Complications | NA | 2.5 [1.6–3.3] (39) | 2.0 [1.5–2.6] (38) | 2.2 [1.9–3.1] (32) |
SVRI (dyn*s/cm5*m2) | ||||
All | NA | 2625 [2250–3415] (90) | 3266 [2302–3903] (87) | 2639 [2044–3193] (66) |
No complications | NA | 2732 [2195–3284] (51) | 3274 [2426–3832] (49) | 2747 [2077–3202] (34) |
Complications | NA | 2364 [1958–3090] (39) | 2939 [2282–3813] (38) | 2643 [1772–3197] (32) |
DO2I (ml/min/m2) | ||||
All | NA | 337 [231–382] (90) | 308 [233–378] (87) | 347 [282–425] (66) |
No complications | NA | 337 [257–377] (51) | 335 [273–381] (49) | 343 [288–409] (34) |
Complications | NA | 341 [218–443] (39) | 306 [241–393] (38) | 344 [281–436] (32) |
O2ER (%) | ||||
All | NA | 26 [22–36] (90) | 30 [26–37] (87) | 29 [25–35] (66) |
No complications | NA | 26 [23–31] (51) | 28 [26–33] (49) | 28 [25–35] (34) |
Complications | NA | 27 [22–38] (39) | 35 [27–42] (38) | 31 [25–35] (32) |
Temperature (°C) | ||||
All | NA | 35.2 [35–36] | 36.0 [35.5–36.8]* | 36.5 [36.0–37.1]* |
No complications | NA | 35.2 [35–36] | 36.0 [35.5–36.9]* | 36.5 [36–37]* |
Complications | NA | 35.5 [35–36] | 36.2 [35.7–36.8]* | 36.7 [36.2–37.3]* |
Mechanical ventilation (n [%]) | ||||
All | – | 90 [100%] | 87 [97%] | 66 [73%] |
No complications | – | 51 [100%] | 49 [96%] | 34 [67%] |
Complications | – | 39 [100%] | 38 [97%] | 32 [82%] |
Vasopressors (n, %) | ||||
All | – | 34 [38%] | 37 [41%] | 33 [37%] |
No complications | – | 16 [31%] | 16 [31%] | 15 [29%] |
Complications | – | 18 [46%] | 21 [54%] | 18 [46%] |
Inotropic drugs (n, %) | ||||
All | – | 24 [27%] | 25 [28%] | 26 [29%] |
No complications | – | 12 [24%] | 12 [24%] | 11 [22%] |
Complications | – | 12 [30%] | 13 [32%] | 15 [37%] |