Effects of dexamethasone on post-operative cognitive dysfunction and delirium in adults following general anaesthesia: a meta-analysis of randomised controlled trials

Table 1 The characteristics of the included studies

Studies ID	Design	Country	Age (min ± SD)		M/F		Type of surgery	Outcome
Studies ID		Country	Dex	Control	Dex	Control
Fang 2014	3-arm RCT	China	48.9± 5.35^a	48.0 ± 5.77	247/388	121/198	microvascular decompression	POCD
Glumac 2017	2-arm RCT	Croatia	63.7± 9.0	64.2± 9.4	63/22	64/20	Cardiac surgery	POCD
Mardani 2013	2-arm RCT	Iran	64.5± 11.10	60.04± 12.77	36/7	44/6	Cardiac surgery	POD
Ottens 2014^b	2-arm RCT	The Netherla-nds	63.4± 12.3	65.4± 1.5	103/37	109/29	Cardiac surgery	POCD
Sauer 2014^b	2-arm RCT	The Netherla-nds	67 ± 12	66 ± 12	255/112	225/145	Cardiac surgery	POD

SD = standard deviation, POCD = postoperative cognitive dysfunction, POD = postoperative delirium, Dex = dexamethasone. ^aThis 3-arm RCT reported the age was 48.9 ± 5.35, 48.0 ± 5.60 in dexamethasone 0.1 mg/kg and dexamethasone 0.2 mg/kg respectively. ^bOttens 2014 and Sauer 2014 were two substudies of a larger, multicenter placebo-controlled randomized clinical trial

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