Different dose regimes and administration methods of tranexamic acid in cardiac surgery: a meta-analysis of randomized trials

Table 1 TXA vs Control for mortality and thrombotic events

Endpoints	Number of studies/reference	Overall participants	Effect estimate (RR, 95% CI)	P	Heterogeneity(I²)
Mortality	29	8907	0.78(0.54, 1.14)	0.20	0%
Stroke	32	9257	0.88(0.61, 1.28)	0.50	0%
Myocardial infarction	32	8688	0.89(0.77, 1.04)	0.67	0%
Pulmonary embolism	18	6587	1.08(0.59,2.00)	0.60	0%
Renal dysfunction	19	7210	0.99(0.77, 1.27)	0.92	0%

ISSN: 1471-2253