Table 1 Characteristics of the studies included in the meta-analysis
Author | Study design | Study Period | Country | Inclusion Criteria | Exclusion Criteria | Outcomes | Type of Endovascular Treatment | Sample Size (GA/CS) | Methodological qualitya |
|---|---|---|---|---|---|---|---|---|---|
Abou-Chebl et al. (2010) | Retrospective cohort study | 2005–2009 | USA | Anterior circulation AIS | Posterior circulation strokes; no intervention was performed | mRS and mortality on day 90 | IA/IV tPA, mechanical thrombectomy, angioplasty | 428/552 | 5 |
Jumaa et al. (2010) | Retrospective cohort study | 2006–2009 | USA | Middle cerebral artery–M1 segment occlusion treated with endovascular therapy | Vertebrobasilar occlusions; internal carotid artery terminus occlusion; M2 occlusion | mRS and mortality on day 90 | IA/IV tPA and mechanical thrombectomy | 53/73 | 7 |
Nichols et al. (2010) | Post hoc analysis of IMS II trial | NA | USA | Anterior circulation strokes and underwent angiography and/or intervention | Data were not available before or after angiography | Recanalization, mRS and mortality on day 90 | IA/IV tPA, low-energy ultrasound | 26/49 | 7 |
Sugg et al. (2010) | Retrospective cohort study | 2007–2009 | USA | AIS and underwent endovascular treatment within 8 h from symptom onset | NA | Recanalization, mRS and mortality on day 90 | Mechanical thrombectomy | 9/57 | 5 |
Davis et al. (2012) | Retrospective cohort study | 2003–2009 | Canada | AIS and received endovascular treatment | Management could not be determined | mRS and mortality on day 90 | IA tPA and mechanical thrombectomy | 48/48 | 7 |
Hassan et al. (2012) | Retrospective cohort study | 2006–2010 | USA | AIS and received endovascular treatment | The infarct burden was greater than or equal to one third of the middle cerebral artery territory | mRS and in-hospital mortality | IV tPA, endovascular technique not specified | 53/83 | 5 |
Langner et al. (2013) | Retrospective cohort study | 2005–2010 | Germany | AIS and treated with endovascular therapy | NA | mRS and mortality | IA tPA and mechanical thrombectomy | 19/105 | 8 |
Abou-Chebl et al. (2014) | Post hoc analysis of NASA registry | NA | North America | AIS and received endovascular treatment within 6 h from symptom onset | NA | mRS and mortality on day 90 | IV tPA, mechanical thrombectomy | 196/85 | 7 |
John, S et al. (2014) | Retrospective cohort study | 2008–2012 | USA | Anterior circulation AIS and treated with endovascular therapy | Posterior circulation AIS | In-hospital mortality and mRS on day 30 | IV tPA, mechanical thrombectomy | 91/99 | 9 |
Li et al. (2014) | Retrospective cohort study | 2006–2012 | USA | AIS and received endovascular treatment | NA | mRS and mortality | IA tPA, mechanical thrombectomy | 35/74 | 8 |
Abou-Chebl et al. (2015) | Post hoc analysis of IMS III trial | 2006–2011 | USA | AIS, received IV tPA within 3 h and received endovascular treatment | Large regions of clear hypodensity on CT scan | mRS and in-hospital mortality | IV/IA tPA and mechanical thrombectomy | 147/269 | 9 |
McDonald J.S et al. (2015) | Retrospective cohort study | 2006–2013 | USA | AIS and received mechanical thrombectomy | Patients who underwent another invasive surgery | In-hospital mortality and complications | IV tPA and mechanical thrombectomy | 507/507 | 7 |
Van Den Berg L.A. et al. (2015) | Retrospective cohort study | 2002–2013 | Netherlands | Anterior circulation AIS | Patients lack of information | mRS and mortality | IA tPA and mechanical thrombectomy | 70/278 | 7 |
Just, C. et al. (2016) | Retrospective cohort study | 2000–2013 | Canada | Underwent neuro-interventional stroke procedure | Aneurysm repair, carotid stenting, extracranial-intracranial bypass | mRS and mortality on day 90 and 180 | IA tPA and mechanical thrombectomy, thromboaspiration | 42/67 | 8 |
Berkhemer OA. et al. (2016) | Post hoc analysis of MR CLEAN | 2010–2014 | Netherlands | AIS patients who received mechanical thrombectomy or intra-arterial thrombolysis | Cerebral hemorrhage, coagulation abnormalities | mRS and mortality on day 90 and 180 | IA tPA and mechanical thrombectomy, thromboaspiration | 79/137 | 9 |
Schönenberger S et al. (2016) | RCT | 2014–2016 | Germany | Severe AIS, NIHSS> 10 | diagnostic imaging results did not clearly depict site of vessel occlusion | NIHSS after 24 h, mRS and mortality on day 90 | IA tPA and angioplasty, mechanical thrombectomy, thromboaspiration | 73/77 | NA |
Bekelis, K. et al. (2017) | Retrospective cohort study | 2009–2013 | USA | AIS patients undergoing mechanical thrombectomy | NA | mortality in hospital | IV tPA, thromboaspiration | 441/733 | 6 |
Lowhagen Henden, P. et al. (2017) | RCT | 2013–2016 | Sweden | Anterior circulation AIS, NIHSS> 10 | Occlusion of posterior cerebral circulation | mRS and mortality on day 90 and 180 | IV tPA, mechanical thrombectomy | 45/45 | NA |
Slezak, A.et al. (2017) | Prospective study | 2010–2015 | Switzerland | Anterior circulation AIS | NA | mRS and mortality on day 90 | IV tPA, mechanical thrombectomy | 266/135 | 7 |
Simonsen, C. Z. et al. (2018) | RCT | 2015–2017 | Denmark | Anterior circulation AIS | Glasgow Coma Scale score < 9 or premorbid mRS score > 2 | mRS and mortality on day 90 and 180 | IA tPA, angioplasty, mechanical thrombectomy | 65/63 | NA |
Peng et al. (2018) | Prospective study | 2015.01–2015.08 | China | Anterior circulation AIS | DWI lesion volume > 50 mL | Rates of successful recanalization and mRS on day 90 | Interventional treatment with Solitaire | 44/105 | 8 |
Omer F. Eker et al. (2018) | Post hoc analysis SWIFT PRIME trial | 2013–2015 | USA and Europe | Anterior circulation AIS | Subject who is contraindicated to IV t-PA | Rates of successful recanalization and mRS on day 90 | Teated with Solitaire RevascularizationDevice and IV-tPA | 32/65 | 8 |
Shanet et al. (2018) | Retrospective cohort study | 2014–2016 | China | Anterior circulation AIS | Received intra-arterial thrombolysis alone, with concomitant aneurysm or arteriovenous malformation | mRS and mortality on day 90 | NA | 114/114 | 8 |