From: Intra-operative red blood cell transfusion and mortality after cardiac surgery
No RBC transfusion | RBC transfusion | Unadjusted | PS adjusted | |
---|---|---|---|---|
(n = 2445) | (n = 488) | p-value | p-value | |
Patient characteristics | ||||
Male gender, n (%) | 2026 (82.9) | 249 (51) | < 0.001 | 0.403 |
Age, yr | 66 (60–73) | 74 (68–79) | < 0.001 | 0.296 |
BMI, kg/m2 | 27 (25–30) | 26 (24–29) | 0.001 | 0.684 |
Smoking, n (%) | 756 (30.9) | 116 (23.8) | 0.002 | 0.795 |
Chronic obstructive pulmonary disease, n (%) | 279 (11.4) | 66 (13.5) | 0.365 | 0.984 |
Hypertension, n (%) | 1466 (60.0) | 321 (65.8) | 0.016 | 0.688 |
Diabetes, n (%) | 567 (23.2) | 166 (34.0) | < 0.001 | 0.617 |
Peripheral artery disease, n (%) | 252 (10.3) | 90 (18.4) | < 0.001 | 0.688 |
Previous stroke, n(%) | 161 (6.6) | 50 (10.2) | 0.004 | 0.708 |
Previous cardiac surgery, n (%) | 60 (2.5) | 33 (6.8) | < 0.001 | 0.894 |
Reduced LVEF (< 50%), n(%) | 572 (23.4) | 157 (32.2) | < 0.001 | 0.835 |
Unstable angina, n (%) | 155 (6.3) | 72 (14.8) | < 0.001 | 0.858 |
Emergency procedure, n (%) | 156 (6.4) | 53 (10.9) | 0.001 | 0.948 |
EuroSCORE | 3 (2–5) | 6 (4–8) | < 0.001 | 0.290 |
Laboratory | ||||
Hb, mmol/l | 8.8 (8.2–9.3) | 7.6 (7.0–8.4) | < 0.001 | 0.029 |
Creatinine, μmol/l | 83 [73–96] | 85 [71–109] | < 0.001 | 0.911 |
Procedural characteristics | ||||
Duration of procedure, min | 190 [161–227] | 223 [186–265] | < 0.001 | 0.652 |
Use of IMA, n (%) | 2251 (92.1) | 412 (84.4) | < 0.001 | 0.927 |
Salvaged red cell volume reinfused (units) | 1.8 [1.0–2.0] | 2.0 [1.0–3.0] | < 0.001 | 0.809 |
CABG, n (%) | 2225 (91.0) | 330 (67.6) | < 0.001 | 0.875 |
CABG + AVR, n (%) | 220 (9.0) | 158 (32.4) | < 0.001 | 0.875 |