Postoperative delirium in critically ill surgical patients: incidence, risk factors, and predictive scores

BMC Anesthesiology

Table 3 Receiver operating characteristic curve analysis

Cut point	Sensitivity (%)	Specificity (%)	PPV	NPV	LR+	LR-	AUC (95% CI)	Youden’s Index
≥ 110	83.61	62.96	42.15	92.25	2.26	0.26	0.73 (0.66–0.80)	0.47
≥ 115	78.69	70.37	46.15	91.10	2.66	0.30	0.75 (0.68–0.82)	0.49
≥ 119	75.41	73.02	47.42	90.20	2.79	0.34	0.74 (0.67–0.82)	0.48
≥ 125	72.13	80.95	55.00	90.00	3.79	0.34	0.77 (0.69–0.84)	0.53
≥ 129	67.21	86.24	61.19	89.07	4.89	0.38	0.77 (0.69–0.84)	0.53
≥ 133	57.38	88.89	62.50	86.60	5.16	0.48	0.73 (0.65–0.81)	0.46

PPV, positive predictive value; NPV, negative predictive value; LR+, positive likelihood ratio; LR-, negative likelihood ratio; AUC, area under curve; 95% CI, 95% confidence interval
The optimum cut-off point to discriminate between a high and low probability of postoperative delirium was 125 with the highest Youden'd Index, the best AUC and the optimum sensitivity and specificity

ISSN: 1471-2253