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Table 1 Baseline characteristics of delirious and non-delirious patients

From: Postoperative delirium in critically ill surgical patients: incidence, risk factors, and predictive scores

Variables

Delirium (n=61)

No delirium (n=189)

P-value

Demographic data

 Age (years)

72.7±11.4

61.4±16.8

<0.001

  ≥ 60

55 (90.2%)

114 (60.3%)

<0.001

 Gender

   

  Male

31 (50.8%)

90 (47.6%)

0.768

 Comorbidities

   

  Hypertension

50 (81.9%)

105 (55.6%)

<0.001

  DM

26 (42.6%)

37 (19.6%)

0.001

  Cardiac disease

21 (34.4%)

43 (22.8%)

0.091

  Previous stroke

15 (24.6%)

18 (9.5%)

0.004

  Modified IQCODE score ≥ 3.42

10 (16.39%)

6 (3.2%)

0.001

  ESRD or CKD stage 4−5

10 (16.4%)

24 (12.7%)

0.520

  Cirrhosis

3 (4.9%)

9 (4.8%)

1.000

 Smoking history pack year

41.9±27.1

24.4±21.6

0.155

  ≥ 30 pack year

10 (16.4%)

20 (10.6%)

0.259

 Current alcohol consumption

6 (9.8%)

11 (5.8%)

0.378

 Coma

17 (27.9%)

16 (8.5%)

<0.001

Intraoperative data

 Emergency Surgery

34 (55.74%)

74 (39.2%)

0.026

 Vascular surgery

20 (32.8%)

32 (16.9%)

0.011

 Non-vascular surgery

  Intra-abdominal

23 (37.7%)

65 (34.4%)

0.646

  Orthopedic

3 (4.9%)

26 (13.8%)

0.068

  Gynecological

3 (4.9%)

23 (12.2%)

0.147

  Other

12 (19.7%)

43 (22.8%)

0.723

 Operation time

193.5±162.6

234.8±178.9

0.111

 Intraoperative blood loss (mL)

250 (60−700)

400 (100−1400)

0.079

 Intraoperative PRC transfusion (mL)

264 (0−663)

0 (0−1023)

0.865

 Hypoxia

3 (4.9%)

7 (3.7%)

0.710

 Intraoperative hypotension

50 (82.0%)

146 (77.3%)

0.480

ICU admission

 Hemoglobin (mg/dL)

10.5±2.5

10.9±2.1

0.156

 Blood sugar at admission (mg/dL)

155.6±42.1

152.2±46.3

0.611

 Serum albumin (mg/dL)

2.7±0.6

2.8±0.7

0.168

 BUN/Cr ratio >20

22 (36.1%)

48 (25.4%)

0.139

 Sepsis

24 (39.3%)

37 (19.6%)

0.003

 APACHE II score

12.1±4.8

8.3±3.9

<0.001

 SOFA score

5.8±3.4

3.4±2.7

<0.001

 Mechanical ventilation

54 (88.5%)

131 (69.2%)

0.002

Medication

 Preoperative-Benzodiazepine

8 (13.1%)

10 (5.3%)

0.049

 Inraoperative-Benzodiazepine

32 (53.3%)

93 (47.7%)

0.658

 Benzodiazepine (Pre and Postoperative)

27 (44.3%)

36 (19.1%)

<0.001

 Preoperative-Opioid

5 (8.2%)

18 (9.5%)

1.000

 Intraoperative-Opioid

58 (96.7%)

176 (94.1%)

0.740

 Opioid (Pre and Postoperative)

59 (96.7%)

184 (97.4%)

1.000

 Postoperative-Propofol use

20 (32.8)

31 (16.4%)

0.010

  1. ESRD, end stage renal disease; CKD, chronic kidney disease; DM, diabetes mellitus; Modified IQCODE score, modified informant questionnaire on cognitive decline in the elderly score; BUN, blood urea nitrogen; Cr, creatinine; APACHE II score, acute physiology and chronic health evaluation II score; SOFA score, sequential organ failure assessment score
  2. Data presented as mean±SD or median (IQR) or N (%)