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Table 1 Patients’ and data characteristics (n = 14)

From: Population pharmacokinetic-pharmacodynamic model of propofol in adolescents undergoing scoliosis surgery with intraoperative wake-up test: a study using Bispectral index and composite auditory evoked potentials as pharmacodynamic endpoints

Gender (M / F)

2 / 12

Age (years)

14.7 (9.8–20.1)

Bodyweight (kg)

51 (36.6–82)

Height (cm)

162.5 (142–183)

Number of blood samples per patient

16 (6–22)

Number of BIS events per patient

113 (66–154)

Number of cAAI events per patient

100 (60–141)

Duration of propofol infusion (minutes)

410.0 (200–460)

Length of wake-up test (minutes)

21.5 (7.6–42.4)

ROC after propofol infusion (minutes)

52.2 (22.6–116.33)

  1. F Female, M Male, BIS Bispectral Index, cAAI composite A-Line ARX Index, ROC Return of consciousness. The length of wake-up test is defined as the length of time propofol infusion was stopped during the intraoperative wake-up test during propofol-remifentanil anesthesia. Data are presented as a median (minimum-maximum)