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Fig. 2 | BMC Anesthesiology

Fig. 2

From: Population pharmacokinetic-pharmacodynamic model of propofol in adolescents undergoing scoliosis surgery with intraoperative wake-up test: a study using Bispectral index and composite auditory evoked potentials as pharmacodynamic endpoints

Fig. 2

Diagnostic plots of the final pharmacokinetic (a and b) and pharmacodynamic models using Bispectral index (BIS) (c and d) and composite A-Line ARX index (cAAI) (e and f), including (left) observations versus individual-predicted propofol concentrations or depth of anesthesia, and (right) observations versus population predicted concentrations or depth of anesthesia. The solid line indicates the trend line, the dashed line represents the line of identity, x = y

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