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Table 3 Transfusion of blood products

From: Association between viscoelastic tests-guided therapy with synthetic factor concentrates and allogenic blood transfusion in liver transplantation: a before-after study

 

Unmatched Cohort (n = 237)

Matched Cohort (n = 135)b

 

Intervention (n = 54)

Control (n = 183)

p valuea

Intervention (n = 46)

Control (n = 89)

p valuea

Transfusion of hemocomponents

 Any transfusion of hemocomponents

19 / 54 (35.2)

103 / 183 (56.3)

0.006

17 / 46 (37.0)

52 / 89 (58.4)

0.018

 Red blood cells

16 / 53 (30.2)

96 / 183 (52.5)

0.004

14 / 45 (31.1)

47 / 89 (52.8)

0.017

 Units transfused

0.7 ± 1.3

1.7 ± 2.7

0.007

0.6 ± 1.0

1.7 ± 2.7

0.008

 Fresh frozen plasma

3 / 53 (5.7)

50 / 183 (27.3)

< 0.001

3 / 45 (6.7)

25 / 89 (28.1)

0.003

 Units transfused

0.2 ± 0.8

2.1 ± 4.2

0.001

0.2 ± 0.9

2.2 ± 4.5

0.004

 Cryoprecipitate

3 / 54 (5.6)

11 / 183 (6.0)

0.900

3 / 46 (6.5)

5 / 89 (5.6)

0.833

 Units transfused

0.4 ± 2.1

0.4 ± 1.8

0.876

0.5 ± 2.3

0.4 ± 1.9

0.938

 Platelets

10 / 54 (18.5)

31 / 183 (16.9)

0.787

10 / 46 (21.7)

16 / 89 (18.0)

0.599

 Units transfused (random)

0.0 ± 0.0

0.1 ± 0.6

0.443

0.0 ± 0.0

0.1 ± 0.6

0.474

 Units transfused (apheresis)

0.2 ± 0.4

0.2 ± 0.4

0.871

0.2 ± 0.4

0.2 ± 0.5

0.963

Transfusion of hemoderivatives

 Any transfusion of hemoderivatives

19 / 54 (35.2)

0 / 183 (0.0)

< 0.001

17 / 46 (37.0)

0 / 89 (0.0)

< 0.001

 Fibrinogen concentrate

18 / 54 (33.3)

0 / 183 (0.0)

< 0.001

16 / 46 (34.8)

0 / 89 (0.0)

< 0.001

 Grams transfused

1.4 ± 2.3

0.0 ± 0.0

< 0.001

1.4 ± 2.4

0.0 ± 0.0

< 0.001

 Prothrombin complex concentrate

6 / 54 (11.1)

0 / 183 (0.0)

< 0.001

5 / 46 (10.9)

0 / 89 (0.0)

0.001

 Units transfused

222.2 ± 711.5

0.0 ± 0.0

< 0.001

195.6 ± 645.3

0.0 ± 0.0

0.005

 Use of antifibrinolytic

8 / 54 (14.8)

77 / 182 (42.3)

< 0.001

7 / 46 (15.2)

36 / 88 (40.9)

< 0.001

 Tranexamic acid

8 / 54 (14.8)

0 / 182 (0.0)

 

7 / 46 (15.2)

0 / 88 (0.0)

 

 Aprotinin

0 / 54 (0.0)

29 / 182 (15.9)

 

0 / 46 (0.0)

15 / 88 (17.0)

 

 Epsilon-aminocaproic acid

0 / 54 (0.0)

48 / 182 (26.4)

 

0 / 46 (0.0)

21 / 88 (23.9)

 
  1. Data presented as mean ± standard deviation or number / total (percentage)
  2. aComparison of differences between the two groups using the t test for continuous variables and the χ2 test for categorical variables
  3. bAdjusted by age, Child, MELD, presence of HCC and pre-transplantation hemoglobin