| Unmatched Cohort (n = 237) | Matched Cohort (n = 135)b | ||||
---|---|---|---|---|---|---|
 | Intervention (n = 54) | Control (n = 183) | p valuea | Intervention (n = 46) | Control (n = 89) | p valuea |
Transfusion of hemocomponents | ||||||
 Any transfusion of hemocomponents | 19 / 54 (35.2) | 103 / 183 (56.3) | 0.006 | 17 / 46 (37.0) | 52 / 89 (58.4) | 0.018 |
 Red blood cells | 16 / 53 (30.2) | 96 / 183 (52.5) | 0.004 | 14 / 45 (31.1) | 47 / 89 (52.8) | 0.017 |
 Units transfused | 0.7 ± 1.3 | 1.7 ± 2.7 | 0.007 | 0.6 ± 1.0 | 1.7 ± 2.7 | 0.008 |
 Fresh frozen plasma | 3 / 53 (5.7) | 50 / 183 (27.3) | < 0.001 | 3 / 45 (6.7) | 25 / 89 (28.1) | 0.003 |
 Units transfused | 0.2 ± 0.8 | 2.1 ± 4.2 | 0.001 | 0.2 ± 0.9 | 2.2 ± 4.5 | 0.004 |
 Cryoprecipitate | 3 / 54 (5.6) | 11 / 183 (6.0) | 0.900 | 3 / 46 (6.5) | 5 / 89 (5.6) | 0.833 |
 Units transfused | 0.4 ± 2.1 | 0.4 ± 1.8 | 0.876 | 0.5 ± 2.3 | 0.4 ± 1.9 | 0.938 |
 Platelets | 10 / 54 (18.5) | 31 / 183 (16.9) | 0.787 | 10 / 46 (21.7) | 16 / 89 (18.0) | 0.599 |
 Units transfused (random) | 0.0 ± 0.0 | 0.1 ± 0.6 | 0.443 | 0.0 ± 0.0 | 0.1 ± 0.6 | 0.474 |
 Units transfused (apheresis) | 0.2 ± 0.4 | 0.2 ± 0.4 | 0.871 | 0.2 ± 0.4 | 0.2 ± 0.5 | 0.963 |
Transfusion of hemoderivatives | ||||||
 Any transfusion of hemoderivatives | 19 / 54 (35.2) | 0 / 183 (0.0) | < 0.001 | 17 / 46 (37.0) | 0 / 89 (0.0) | < 0.001 |
 Fibrinogen concentrate | 18 / 54 (33.3) | 0 / 183 (0.0) | < 0.001 | 16 / 46 (34.8) | 0 / 89 (0.0) | < 0.001 |
 Grams transfused | 1.4 ± 2.3 | 0.0 ± 0.0 | < 0.001 | 1.4 ± 2.4 | 0.0 ± 0.0 | < 0.001 |
 Prothrombin complex concentrate | 6 / 54 (11.1) | 0 / 183 (0.0) | < 0.001 | 5 / 46 (10.9) | 0 / 89 (0.0) | 0.001 |
 Units transfused | 222.2 ± 711.5 | 0.0 ± 0.0 | < 0.001 | 195.6 ± 645.3 | 0.0 ± 0.0 | 0.005 |
 Use of antifibrinolytic | 8 / 54 (14.8) | 77 / 182 (42.3) | < 0.001 | 7 / 46 (15.2) | 36 / 88 (40.9) | < 0.001 |
 Tranexamic acid | 8 / 54 (14.8) | 0 / 182 (0.0) |  | 7 / 46 (15.2) | 0 / 88 (0.0) |  |
 Aprotinin | 0 / 54 (0.0) | 29 / 182 (15.9) |  | 0 / 46 (0.0) | 15 / 88 (17.0) |  |
 Epsilon-aminocaproic acid | 0 / 54 (0.0) | 48 / 182 (26.4) |  | 0 / 46 (0.0) | 21 / 88 (23.9) |  |