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Table 2 Postoperative and surgical characteristics

From: Association between viscoelastic tests-guided therapy with synthetic factor concentrates and allogenic blood transfusion in liver transplantation: a before-after study

 

Unmatched Cohort (n = 237)

Matched Cohort (n = 135)b

 

Intervention (n = 54)

Control (n = 183)

p valuea

Intervention (n = 46)

Control (n = 89)

p valuea

General characteristics of the surgery

 Technique

  

0.586

  

0.978

 Piggy-back

53 / 54 (98.1)

177 / 183 (96.7)

 

45 / 46 (97.8)

87 / 89 (97.8)

 

 Conventional

1 / 54 (1.9)

6 / 183 (3.3)

 

1 / 46 (2.2)

2 / 89 (2.2)

 

 Clamping time, minutes

38.1 ± 10.3

64.8 ± 90.0

0.032

38.3 ± 10.6

52.4 ± 17.9

< 0.001

 Ischemia time, minutes

418.3 ± 69.2

569.9 ± 165.8

< 0.001

421.0 ± 71.8

584.4 ± 161.3

< 0.001

Use of fluids, urine output and cell-saver

 Total fluid infusion, mL

3846.3 ± 1124.01

4986.7 ± 1811.3

< 0.001

3743.5 ± 956.7

4946.9 ± 1734.6

< 0.001

 Lactated ringer, mL

0.0 ± 0.0

710.1 ± 1524.2

0.001

0.0 ± 0.0

398.9 ± 991.9

0.007

 Normal saline, mL

0.0 ± 0.0

118.8 ± 510.7

0.089

0.0 ± 0.0

134.8 ± 542.3

0.095

 Plasma-Lyte®, mL

3570.4 ± 1055.7

3733.1 ± 2171.5

0.595

3484.8 ± 925.9

4000.0 ± 2012.7

0.102

 Albumin, mL

275.9 ± 134.9

424.7 ± 317.5

0.001

258.7 ± 118.1

413.2 ± 173.5

< 0.001

 Cell-saver, mL

522.4 ± 713.6

568.0 ± 968.0

0.748

585.0 ± 734.8

653.6 ± 1066.8

0.697

 Urine output, mL

611.3 ± 510.1

722.1 ± 431.4

0.117

644.4 ± 529.7

722.1 ± 441.8

0.372

 Fluid balance, mL

3248.1 ± 1212.0

4254.3 ± 1737.6

< 0.001

3112.2 ± 1021.5

4237.2 ± 1689.9

< 0.001

Vital signs and vasopressors

Induction

 Heart rate, bpm

75.3 ± 13.9

78.9 ± 14.9

0.117

76.1 ± 13.1

79.6 ± 15.1

0.188

 Systolic pressure, mmHg

118.7 ± 26.9

117.8 ± 20.9

0.808

120.2 ± 26.8

118.5 ± 19.0

0.674

 Diastolic pressure, mmHg

62.5 ± 14.5

61.3 ± 13.1

0.546

63.8 ± 14.3

61.0 ± 13.4

0.258

 Mean arterial pressure, mmHg

80.7 ± 17.7

80.3 ± 16.2

0.877

81.4 ± 17.8

79.8 ± 15.3

0.569

 Central venous pressure, mmHg

10.2 ± 3.7

12.8 ± 4.0

< 0.001

10.1 ± 3.9

12.9 ± 3.9

0.001

 Temperature, °C

36.1 ± 0.4

36.2 ± 0.6

0.574

36.2 ± 0.4

36.1 ± 0.6

0.841

 Dopamine, μg/kg/min

0.00 ± 0.00

0.02 ± 0.14

0.275

0.00 ± 0.00

0.01 ± 0.10

0.474

 Norepinephrine, μg/kg/min

0.00 ± 0.00

0.00 ± 0.04

0.271

0.00 ± 0.00

0.00 ± 0.03

0.282

 Dobutamine, μg/kg/min

0.00 ± 0.00

0.03 ± 0.51

0.588

0.00 ± 0.00

0.00 ± 0.00

–

At the end

 Heart rate, bpm

84.7 ± 19.6

95.6 ± 17.7

< 0.001

84.1 ± 19.8

95.5 ± 18.8

0.001

 Systolic pressure, mmHg

118.4 ± 20.7

113.4 ± 16.3

0.063

117.7 ± 21.6

114.2 ± 16.7

0.297

 Diastolic pressure, mmHg

61.5 ± 11.4

57.0 ± 11.0

0.010

60.6 ± 10.7

57.2 ± 11.2

0.092

 Mean arterial pressure, mmHg

80.4 ± 13.8

76.1 ± 12.9

0.036

80.0 ± 13.9

76.5 ± 12.1

0.127

 Central venous pressure, mmHg

9.3 ± 4.7

11.0 ± 2.7

0.001

9.6 ± 4.4

10.9 ± 2.9

0.043

 Temperature, °C

36.1 ± 0.6

37.5 ± 0.5

< 0.001

36.1 ± 0.6

37.5 ± 0.6

< 0.001

 Dopamine, μg/kg/min

0.00 ± 0.00

0.01 ± 0.13

0.346

0.00 ± 0.00

0.00 ± 0.00

–

 Norepinephrine, μg/kg/min

0.06 ± 0.12

0.02 ± 0.05

< 0.001

0.06 ± 0.11

0.02 ± 0.04

< 0.001

 Dobutamine, μg/kg/min

0.13 ± 1.02

0.29 ± 1.24

0.392

0.16 ± 1.10

0.24 ± 1.16

0.686

  1. mL: milliliters; bpm: beats per minute
  2. Data presented as mean ± standard deviation or number / total (percentage)
  3. aComparison of differences between the two groups using the t test for continuous variables and the χ2 test for categorical variables
  4. bAdjusted by age, Child, MELD, presence of HCC and pre-transplantation hemoglobin