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Table 1 Comparison of baseline patient demographic characteristics between operating room and NICU groups

From: A comparison of postoperative outcomes with PDA ligation in the OR versus the NICU: a retrospective cohort study on the risks of transport

 

OR (n = 89)

NICU (n = 100)

Mixed Effect Models with Site Random Effect and Location

Mixed Effect Models with Site Random Effect, Location, Weight at Procedure and Number of Preoperative Comorbidities

Mixed Effect Model with Site Random Effect, Location and Propensity Score

Mean (SD)

Mean (SD)

Mean Difference (95% CI)

p-value

Mean Difference (95% CI)

p-value

Mean Difference (95% CI)

p-value

Birthweight (grams)a

929 (354)

771 (200)

0.23 (0.09, 0.36)

0.001

0.11 (−0.02, 0.23)

0.099

0.13 (0.01, 0.25)

0.032

Gestational Age at Birth (weeks)a

26.6 (3.0)

25.5 (2.0)

0.07 (0.03, 0.11)

< 0.001

0.03 (0.00, 0.07)

0.066

0.04 (0.00, 0.08)

0.029

Weight at Time of Procedure (grams)a

1252 (683)

864 (258)

0.30 (0.20, 0.41)

< 0.001

0.05 (0.01, 0.08)

0.016

0.10 (0.01, 0.19)

0.033

CGA at Time of Procedure (weeks)a

30.6 (4.4)

27.5 (2.2)

3.18 (2.21, 4.16)

< 0.001

0.92 (0.41, 1.42)

< 0.001

1.22 (0.37, 2.06)

0.005

Number of Preoperative Comorbidities

2.94 (1.5)

2.68 (1.3)

0.26 (−0.14, 0.67)

0.201

0.14 (−0.29–0.57)b

0.518b

0.07 (−0.37–0.52)

0.742

Inotrope Scorea

2.8 (4.6)

4.9 (9.8)

−0.60 (− 1.06, − 0.14)

0.011

−0.46 (− 0.94, 0.01)

0.057

−0.43 (− 0.90, 0.05)

0.078

 

OR (n = 89)

NICU (n = 100)

Mixed Effect Models with Site Random Effect and Location

Mixed Effect Models with Site Random Effect, Location, Weight at Procedure and Number of Preoperative Comorbidities

Mixed Effect Model with Site Random Effect, Location and Propensity Score

 

# (%)

# (%)

Odds Ratio (95% CI)

p-value

Odds Ratio (95% CI)

p-value

Odds Ratio (95% CI)

p-value

Number Requiring Inotropes (%)

34 (38%)

39 (39%)

0.73 (0.19, 2.82)

0.650

0.74 (0.18, 3.13)

0.683

0.63 (0.14, 2.80)

0.597

Number of Males (%)

51 (57.3%)

54 (54%)

1.09 (0.45, 2.63)

0.845

1.27 (0.51, 3.17)

0.613

1.58 (0.55, 4.57)

0.687

Ventilatory Requirements Prior to Procedure

   

0.001

 

0.005

 

0.006

Spontaneous

18 (20.2%)

1 (1%)

25.11 (3.23, 195.07)

0.002

10.38 (1.22, 88.32)

0.032

9.19 (1.09, 77.72)

0.042

NIMV

4 (4.5%)

4 (4%)

1.13 (0.27, 4.70)

0.866

1.10 (0.23, 5.17)

0.908

0.83 (0.17, 4.02)

0.811

Conventional

66 (74.2%)

46 (46%)

3.37 (1.81, 6.26)

< 0.001

5.53 (2.65, 11.51)

< 0.001

4.98 (2.38, 10.39)

< 0.001

HFOV/HFJV

1 (1.1%)

49 (49%)

0.01 (0.00, 0.09)

< 0.001

0.01 (0.00, 0.11)

< 0.001

0.02 (0.00, 0.12)

< 0.001

  1. alog transformation of this variable was performed
  2. bNumber of preoperative comorbidities was omitted as a predictor from the model for this particular variable
  3. Clinical data on the 189 premature infants who had PDA ligations performed in the operating room (OR) or the neonatal intensive care unit (NICU). For continuous variables, standard deviations are listed in parentheses. For categorical variables, the number of cases is given, followed by the percentage in parentheses. Abbreviations used: CGA corrected gestational age (estimated post-conceptual age weeks + post-natal age weeks), NIMV noninvasive mechanical ventilation, HFOV high frequency oscillatory ventilation, HFJV high frequency jet ventilation