OR (n = 89) | NICU (n = 100) | Mixed Effect Models with Site Random Effect and Location | Mixed Effect Models with Site Random Effect, Location, Weight at Procedure and Number of Preoperative Comorbidities | Mixed Effect Model with Site Random Effect, Location and Propensity Score | ||||
Mean (SD) | Mean (SD) | Mean Difference (95% CI) | p-value | Mean Difference (95% CI) | p-value | Mean Difference (95% CI) | p-value | |
Birthweight (grams)a | 929 (354) | 771 (200) | 0.23 (0.09, 0.36) | 0.001 | 0.11 (−0.02, 0.23) | 0.099 | 0.13 (0.01, 0.25) | 0.032 |
Gestational Age at Birth (weeks)a | 26.6 (3.0) | 25.5 (2.0) | 0.07 (0.03, 0.11) | < 0.001 | 0.03 (0.00, 0.07) | 0.066 | 0.04 (0.00, 0.08) | 0.029 |
Weight at Time of Procedure (grams)a | 1252 (683) | 864 (258) | 0.30 (0.20, 0.41) | < 0.001 | 0.05 (0.01, 0.08) | 0.016 | 0.10 (0.01, 0.19) | 0.033 |
CGA at Time of Procedure (weeks)a | 30.6 (4.4) | 27.5 (2.2) | 3.18 (2.21, 4.16) | < 0.001 | 0.92 (0.41, 1.42) | < 0.001 | 1.22 (0.37, 2.06) | 0.005 |
Number of Preoperative Comorbidities | 2.94 (1.5) | 2.68 (1.3) | 0.26 (−0.14, 0.67) | 0.201 | 0.14 (−0.29–0.57)b | 0.518b | 0.07 (−0.37–0.52) | 0.742 |
Inotrope Scorea | 2.8 (4.6) | 4.9 (9.8) | −0.60 (− 1.06, − 0.14) | 0.011 | −0.46 (− 0.94, 0.01) | 0.057 | −0.43 (− 0.90, 0.05) | 0.078 |
OR (n = 89) | NICU (n = 100) | Mixed Effect Models with Site Random Effect and Location | Mixed Effect Models with Site Random Effect, Location, Weight at Procedure and Number of Preoperative Comorbidities | Mixed Effect Model with Site Random Effect, Location and Propensity Score | ||||
# (%) | # (%) | Odds Ratio (95% CI) | p-value | Odds Ratio (95% CI) | p-value | Odds Ratio (95% CI) | p-value | |
Number Requiring Inotropes (%) | 34 (38%) | 39 (39%) | 0.73 (0.19, 2.82) | 0.650 | 0.74 (0.18, 3.13) | 0.683 | 0.63 (0.14, 2.80) | 0.597 |
Number of Males (%) | 51 (57.3%) | 54 (54%) | 1.09 (0.45, 2.63) | 0.845 | 1.27 (0.51, 3.17) | 0.613 | 1.58 (0.55, 4.57) | 0.687 |
Ventilatory Requirements Prior to Procedure | 0.001 | 0.005 | 0.006 | |||||
Spontaneous | 18 (20.2%) | 1 (1%) | 25.11 (3.23, 195.07) | 0.002 | 10.38 (1.22, 88.32) | 0.032 | 9.19 (1.09, 77.72) | 0.042 |
NIMV | 4 (4.5%) | 4 (4%) | 1.13 (0.27, 4.70) | 0.866 | 1.10 (0.23, 5.17) | 0.908 | 0.83 (0.17, 4.02) | 0.811 |
Conventional | 66 (74.2%) | 46 (46%) | 3.37 (1.81, 6.26) | < 0.001 | 5.53 (2.65, 11.51) | < 0.001 | 4.98 (2.38, 10.39) | < 0.001 |
HFOV/HFJV | 1 (1.1%) | 49 (49%) | 0.01 (0.00, 0.09) | < 0.001 | 0.01 (0.00, 0.11) | < 0.001 | 0.02 (0.00, 0.12) | < 0.001 |