Fig. 2From: Antiarrhythmic effect of sevoflurane as an additive to HTK solution on reperfusion arrhythmias induced by hypothermia and ischaemia is associated with the phosphorylation of connexin 43 at serine 368HE and TUNEL staining in myocardial tissue (400×). Apoptotic nuclei were identified by TUNEL staining (red), and total nuclei were identified by DAPI counterstaining (blue). a Part of the cardiac muscle fibres appeared broken, swollen and disordered; the black arrow indicates fractured cardiac muscle fibres in the control. b Pathological damage to the myocardium was ameliorated in donor hearts stored in Sevo-HTK solution. c and d Show that the number of apoptotic nuclei increased in the Control group. e and f Show that the number of apoptotic nuclei decreased in the Sevo-HTK group. g Sevoflurane as an additive appreciably lowered the number of apoptotic cells. h Difference between the graft re-beating times in the two groupsBack to article page