Table 3 Independent predictors of vasoplegia using previous definitions of vasoplegia and the unified definition
Argenziano | Â | Univariable | Multivariable | ||||
Preoperative characteristics | No vasoplegia n = 90 | Vasoplegia n = 28 | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value |
Pre-op dobutamine | 43 (47.8%) | 19 (67.9%) | 0.04 | 2.65 (1.05–6.68) | 0.04 | 2.65 (1.05–6.68) | 0.04 |
Pre-op VIS | 4.3 [0.0–7.3] | 6.5 [4.0–11.9] | 0.03 | 1.03 (1.00–1.06) | 0.05 |  |  |
Neutrophil/ Lymphocyt –ratio | 4.5 [3.6–7.7] | 8.0 [5.6–9.5] | 0.04 | 1.13 (1.00 1.28) | 0.05 |  |  |
Levin | Â | Univariable | Multivariable | ||||
Preoperative characteristics | No vasoplegia n = 115 | Vasoplegia n = 3 | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value |
NCCMP | 3 (2.6%) | 2 (66.7%) | <  0.01 | 74.67 (5.22–1067.12) | <  0.01 |  | 1.00 |
DCMP | 85 (73.9%) | 0 (0.0%) | <  0.01 | 0.0 (0.0-∞) | 1.00 |  |  |
Clopidogrel | 6 (5.2%) | 1 (33.3%) | 0.04 | 9.08 (0.71–114.92) | 0.09 |  |  |
Insuline | 4 (3.5%) | 1 (33.3%) | 0.01 | 13.88 (1.03–186.60) | <  0.05 |  | 1.00 |
Preop norepinephrine | 12 (10.4%) | 3 (100%) | <  0.01 | 17.17 (1.45–203.67) | 0.02 |  | 1.00 |
Lactate | 1.9 [1.4–2.7] | 13.1 | 0.03 | ∞ (0.00-∞) | 0.98 |  |  |
Patarroyo | Â | Univariable | Multivariable | ||||
Preoperative characteristics | No vasoplegia n = 109 | Vasoplegia n = 9 | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value |
Previous CT-surgery | 10 (9.2%) | 4 (44.4%) | <  0.01 | 7.92 (1.83–34.30) | <  0.01 | 10.4 (2.04–53.08) | <  0.01 |
Pre-op dopamine | 22 (20.2%) | 5 (55.5%) | 0.02 | 4.94 (1.22–19.96) | 0.03 | 6.46 (1.36–30.55) | 0.02 |
Unified definition | Â | Univariable | Multivariable | ||||
Preoperative characteristics | No vasoplegia n = 79 | Vasoplegia n = 39 | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value |
Previous CT-surgery | 5 (6.3%) | 9 (23.1%) | <  0.01 | 4.44 (1.38–14.34) | 0.01 | 7.60 (1.98–29.24) | <  0.01 |
Euroscore II* | 20.6 [15.3–25.1] | 32.6 [20.6–42.2] | <  0.01 | 1.06 (1.03–1.10) | <  0.01 |  |  |
Pre-op dopamine | 13 (16.5%) | 14 (35.9%) | 0.02 | 2.84 (1.17–6.88) | 0.02 | 3.83 (1.28–11.46) | 0.02 |
Pre-op VIS | 4.1 [0.0–6.7] | 6.5 [4.0–10.6] | <  0.01 | 1.04 (1.00–1.08) | 0.06 |  |  |
Bilirubin (μmol·l−1) | 27.0 [15.5–37.3] | 36.0 [25.0–44.5] | <  0.01 | 1.04 (1.01–1.07) | <  0.01 | 1.04 (1.01–2.08) | <  0.01 |
Creatinine* (μmol·l−1) | 101 [91–150] | 157 [117–186] | 0.02 | 1.01 (1.01–1.02) | <  0.01 |  |  |
Creatinine Clearance (ml·min− 1) | 72 ± 29 | 57 ± 22 | <  0.01 | 0.97 (0.95–0.99) | <  0.01 | 0.97 (0.95–0.99) | <  0.01 |