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Table 2 Clinical history and anesthetic practice of perioperative patients according to hemodynamic fluctuation status (n = 2097)

From: Prediction of hemodynamic fluctuations after induction of general anesthesia using propofol in non-cardiac surgery: a retrospective cohort study

Variables

Hemodynamic fluctuation

P value

≥30%

(n = 482)

No. a

< 30%

(n = 1615)

No. a

Clinical history, n (%)

 Diabetes mellitus

97 (20.1)

0

263 (16.3)

3

0.05

 Hyperlipidemia

108 (22.4)

0

309 (19.2)

3

0.12

 Hypertension

208 (43.2)

0

673 (41.2)

3

0.58

 Ischemic heart disease

33 (6.9)

4

65 (4.0)

7

0.01

 Congestive heart failure

5 (1.0)

0

18 (1.1)

3

0.88

 Arrhythmia

19 (3.9)

0

70 (4.3)

3

0.70

 Valvular heart disease

17 (3.5)

0

76 (4.7)

3

0.27

 Cardiomyopathy

1 (0.2)

0

11 (0.7)

3

0.32b

 Pulmonary hypertension

3 (0.6)

0

7 (0.4)

3

0.71b

 Peripheral vascular disease

13 (2.7)

0

25 (1.6)

3

0.10

 Aortic aneurysm

6 (1.2)

0

9 (0.6)

3

0.12

 Stroke

35 (7.3)

0

84 (5.2)

3

0.09

 Asthma

32 (6.6)

0

118 (7.3)

3

0.61

 Sleep apnea syndrome

22 (4.6)

3

71 (4.4)

12

0.88

 Chronic kidney disease

120 (25.1)

3

368 (22.9)

6

0.32

 Liver dysfunction

9 (1.9)

5

28 (1.8)

16

0.84

 Hyperthyroidism

4 (0.8)

1

12 (0.7)

3

0.85

 Hypothyroidism

18 (3.7)

0

47 (2.9)

0

0.36

 Rheumatoid arthritis

7 (1.5)

1

16 (1.0)

5

0.39

 Gastrointestinal disorder

28 (5.8)

0

92 (5.7)

3

0.93

Operation and anesthesia, n (%)

 Emergency surgery

31 (6.4)

0

96 (5.9)

0

0.69

 Combined epidural anesthesia

206 (42.7)

0

646 (40.0)

0

0.28

 Anesthesia start time, n (%)

 

0

 

0

0.17

  A.M.

294 (61.0)

 

1041 (64.5)

  

  P.M.

188 (39.0)

 

574 (35.5)

  

 Intubation method, n (%)

 

3

 

14

0.68

  Direct

406 (84.8)

 

1369 (85.5)

  

  Video laryngoscope

73 (15.2)

 

232 (14.5)

  

 Operator of intubation, n (%)

 

0

 

0

0.61

 Specialist

137 (23.7)

 

440 (76.3)

  

 Residents

345 (22.7)

 

1175 (77.3)

  

Drug dosage at induction and intubation, mean (95%CI) or median (range)

 Propofol (mg/kg)

1.8 (1.7–1.8)

0

1.9 (1.9–1.9)

0

< 0.001

 Fentanyl (μg/kg)

1.2 (1.2–1.3)

0

1.3 (1.3–1.3)

0

0.02

 Remifentanil (μg kg−1 min−1)

0.2 (0–0.5)

0

0.2 (0–0.5)

0

0.29

 Sevoflurane (%)

0 (0–3.3)

0

0 (0–6.2)

0

0.70c

 Desflurane (%)

0 (0–5.0)

0

0 (0–8.0)

1

0.74c

 Midazolam (%)

0 (0–5.0)

0

0 (0–4.0)

1

0.17c

 Vasopressor, n (%)

19 (3.9)

0

51 (3.2)

0

0.40

  1. Data are presented as n (%) for categorical variables, mean (95%CI) or median (range) for continuous variables
  2. A.M. Ante meridian, P.M. Post meridian, CI Confidence interval
  3. aNumber of missing patients
  4. bFisher’s exact test
  5. cMann-Whitney U test