Levosimendan is superior to epinephrine on coronary flow for lipid-base resuscitation of bupivacaine-induced asystole in the isolated rat heart

Table 1 Baseline Values of Key Variables and weight for control, epinphrine and levosimendan groups

	Control	Epinephrine	Levosimendan	P
Weight(g)	289 ± 10	287 ± 6	288 ± 6	0.940
HR(beats/min)	287 ± 10	285 ± 10	285 ± 6	0.913
LvdevP(mm Hg)	140 ± 10	139 ± 10	137 ± 6	0.768
RPP(mm Hg·beats/min)	40,183 ± 2279	39,461 ± 2073	39,101 ± 2092	0.599
+dP/dt_max (mm Hg/s)	4152 ± 358	4189 ± 214	4141 ± 248	0.704
CF(ml/min)	20.5 ± 0.9	21.3 ± 0.9	21.4 ± 0.7	0.089
Ts(s)	33 ± 6	36 ± 11	34 ± 8	0.188

Values are given as the mean ± standard deviation, n = 8 in each group. Baseline values for major variables showed no significant differences among the 3 groups. Control: lipid only; Epinephrine: combined epinephrine+ lipid; Levosimendan: combined levosimendan + lipid. HR: heart rate; LVdevP: left ventricular developed pressure; RPP: rate-pressure product; +dP/dt_max: maximum change rate of left ventricular pressure increase and decrease; CF: coronary flow; T_asystole: the time from initiation to asystole

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