Skip to main content

Table 4 Side effects / Clinical parameters

From: Programmed intermittent epidural bolus versus continuous epidural infusion for postoperative analgesia after major abdominal and gynecological cancer surgery: a randomized, triple-blinded clinical trial

 

Group CEI (n = 40)

Group PIEB (n = 44)

p-value

Vasopressor need d0, % (yes/no)

7.5 (3/37)

6.8 (3/41)

0.88

Vasopressor need d1, % (yes/no)

2.5 (1/39)

4.5 (2/42)

0.62

Vasopressor need d2, % (yes/no)

0 (0/40)

0 (0/44)

1.00

Nausea d0, % (yes/no)

20 (8/32)

18.2 (8/36)

0.79

Nausea d1, % (yes/no)

22.5 (9/31)

25 (11/33)

0.79

Nausea d2, % (yes/no)

32.5 (13/27)

13.6 (6/38)

0.04

Vomiting d0, % (yes/no)

17.5 (7/33)

11.4 (5/39)

0.40

Vomiting d1, % (yes/no)

20 (8/32)

22.7 (10/34)

0.76

Vomiting d2, % (yes/no)

17.5 (7/33)

15.9 (7/37)

0.85

Satisfaction d0, NRS

10 (10–10)

10 (10–10)

0.15

Satisfaction d1, NRS

10 (10–10)

10 (9–10)

0.19

Satisfaction d2, NRS

10 (8–10)

10 (8–10)

0.84

EDA catheter removal, day

5 (5–7)

5 (5–6)

0.33

Time to first flatus, hours

22.8 (18.6–43.8)

23.1(20.3–45.5)

0.25

Time to first defecation, hours

71.2 (40.8–119)

65.8(32.4–93.5)

0.54

  1. Values are expressed as the median (25th–75th percentiles) or numbers (percents) and as two-sided p-value of the Mann-Whitney –U test or Fisher’s exact test when appropriate. Uncorrected p-values are displayed. Level of significance p < 0.05. NRS numeric rating scale, d0–3 postoperative day 0–3, LA local anaesthetic, EDA epidural anesthesia