Skip to main content

Table 1 Comparison between hypoxemia and non-hypoxemia groups

From: Nomogram for the prediction of postoperative hypoxemia in patients with acute aortic dissection

 

Total (n = 211)

Non-hypoxemia (n = 168)

Hypoxemia (n = 43)

p

Demographics

 Age, median (IQR) (years)

50 (43,63)

50 (42,64)

52 (46.5,59)

0.654

 Male, n (%)

151 (0.72)

116 (0.69)

35 (0.81)

0.158

 Height, median (IQR) (cm)

170 (163,174)

170 (162.75,174)

169 (165,174)

0.647

 Weight, median (IQR) (kg)

70 (62,80)

70 (60,80)

80 (65,89.5)

0.005

 BMI, mean ± SD (kg/m2)

25.32 ± 3.92

24.94 ± 3.86

26.82 ± 3.84

0.006

 Smoking history, n (%)

59 (28)

47 (28)

12 (28)

0.998

 Hypertension, n (%)

134 (64)

102 (61)

32 (74)

0.137

 Diabetes, n (%)

13 (6)

11 (7)

2 (5)

0.998

 Stanford A, n (%)

133 (63)

97 (0.58)

36 (84)

0.003

 Emergency admission, n (%)

188 (89)

145 (86)

43 (1)

0.005

Laboratory tests before operation

 Albumin, mean ± SD (mg/l)

36.6 ± 4.65

36.75 ± 4.76

36 ± 4.22

0.316

 Hematocrit, mean ± SD (%)

36.09 ± 5.71

36.26 ± 5.4

35.41 ± 6.82

0.452

 pH, median (IQR)

7.37 (7.34,7.4)

7.37 (7.34,7.4)

7.37 (7.32,7.38)

0.205

 Lactate, median (IQR) (mmol/l)

2.1 (1.5,2.9)

2.05 (1.48,2.8)

2.30 (1.9,3.1)

0.082

 PaCO2, median (IQR) (mmHg)

41 (37.55,45.55)

41 (37.88,45.23)

40.9 (36.5,47.7)

0.916

 P/F ratio, median (IQR)

235 (176,355)

249 (183.75,367.25)

174 (148.5237)

< 0.001

 Scr, median (IQR) (mmol/l)

81 (64,113)

76.5 (61,104)

103 (77.5145)

< 0.001

 Total bilirubin, median (IQR) (mmol/l)

13.7 (10,22.25)

13.2 (9.57,18.9)

16.7 (11.9,25)

0.016

 WBC, median (IQR) (^109/l)

9.5 (7.4,12.6)

8.9 (6.8,11.65)

12.9 (9.3,15.5)

< 0.001

 CRP, median (IQR) (mg/l)

28.3 (5.75,68.75)

23.4 (4.57,60.38)

58.9 (10.6118.3)

0.003

 Troponin, median (IQR) (ng/ml)

0.01 (0.01,0.01)

0.01 (0.01,0.01)

0.01 (0.01,0.12)

0.028

 CK, median (IQR) (U/l)

78 (51,150.5)

72 (48.75,136.25)

109 (62,228)

0.023

 CKMB, median (IQR) (U/l)

10 (8,16)

10 (8,16)

10 (6.5,14.5)

0.249

 LDH, median (IQR) (U/l)

218 (171,283)

208.5 (165,274.25)

253 (196.5312.5)

0.013

 AST, median (IQR) (U/l)

22 (16.5,34.5)

21 (15,31.25)

31 (18.5,44.5)

0.007

Intraoperative variables

 Aortic clamping time, mean ± SD (min)

127.91 ± 40.82

128.84 ± 40.7

124.26 ± 41.59

0.519

 CBP time, median (IQR) (min)

178 (140,211)

180 (146.75,210)

169 (132.5221)

0.749

 Duration of operation, median (IQR) min

295 (120,390)

285 (90,390)

300 (242.5420)

0.072

 Minimum temperature, median (IQR) (°C)

36.2 (35.6,36.55)

36.2 (35.4,36.6)

36.3 (36,36.5)

0.250

 Input, median (IQR) (ml)

6250 (5150,7587.5)

6090 (5150,7332.5)

6380 (4775,8170)

0.651

 Output, median (IQR) (ml)

4850 (3600,5800)

4900 (3575,6000)

4500 (3675,5600)

0.358

Clinical outcomes

 LOS in ICU, median (IQR) (days)

7 (4,12)

7 (4,11)

10 (5.5,14)

0.079

 LOS in hospital, median (IQR) (days)

19 (13,24.5)

19 (13,25)

18 (12.5,24)

0.775

 Duration of MV, median (IQR) (hours)

15 (5,82)

12 (3.75,70.25)

41 (10.5140)

0.002

 Mortality, n (%)

7 (3)

6 (4)

1 (2)

0.997

  1. Note: continuous variables were expressed as mean and standard deviation for normal data, and as median and interquartile range for non-normal data. Categorical variables were expressed as number and percentage. Comparisons between hypoxemia and non-hypoxemia groups were performed using student t test or rank sum test as appropriate. Chi-square or Fisher’s exact test was employed for categorical variables
  2. Abbreviations: No. number, Prop. proportion, ICU intensive care unit, LOS length of stay, WBC white blood cell count, CRP c-reactive protein, Scr serum creatinine, BMI body mass index, CK creatine kinase, CKMB creatine kinase isoenzymes, LDH lactate dehydrogenase, AST aspartate aminotransferase, MV mechanical ventilation, CPB cardiopulmonary bypass, IQR interquartile range, SD standard deviation