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Table 4 Cost elements of anesthesia I – group SEVO compared to SEVO+ and group PROP compared to PROP+

From: Cost-effectiveness of anesthesia maintained with sevoflurane or propofol with and without additional monitoring: a prospective, randomized controlled trial

Costs

SEVO (n = 30)

SEVO+ (n = 30)

p value

PROP (n = 30)

PROP+ (n = 29)

p value

and in group PROP(€)

 Fentanyl

0.19 ± 0.03

0.20 ± 0.03

1.000

0.19 ± 0.02

0.20 ± 0.02

1.000

 Propofol

1.16 ± 0.16

0.94 ± 0.19

0.016

1.14 ± 0.08

0.81 ± 0.20

<  0.001

 Atracurium

2.44 ± 0.27

2.37 ± 0.42

1.000

2.22 ± 0.55

2.30 ± 0.36

1.000

Conduct of anesthesia (€/hour)

 Fentanyl

0.12 ± 0.08

0.12 ± 0.09

1.000

0.18 ± 0.08

0.20 ± 0.07

0.996

 Sevoflurane

4.62 ± 2.03

4.12 ± 1.61

0.864

 

 Propofol

 

3.39 ± 0.91

3.08 ± 0.85

1.000

 Atracurium

0.58 ± 0.40

0.52 ± 0.42

0.292

0.67 ± 0.55

0.56 ± 0.39

1.000

 Other drugs (€/hour)

1.51 ± 2.14

1.22 ± 1.99

1.000

1.83 ± 1.15

1.60 ± 2.01

0.572

Summary of costs

 Total drug (€/hour)

8.84 ± 4.11

7.86 ± 3.54

0.002

8.33 ± 3.02

7.52 ± 2.49

<  0.001

 Total disposables (€)

6.49 ± 0.11

23.25 ± 0.12

<  0.001

8.09 ± 0.07

24.76 ± 0.19

<  0.001

 Total cost of anesthesia (€/hour)

12.15 ± 5.32

19.95 ± 8.53

< 0.001

13.23 ± 4.23

22.11 ± 8.08

< 0.001

  1. Values were expressed as mean ± standard deviation; SEVO Sevoflurane anesthesia without additional monitoring; SEVO+ Sevoflurane anesthesia with BIS and TOF monitoring; PROP Propofol anesthesia without additional monitoring; PROP+ Propofol anesthesia with BIS and TOF monitoring; Other drugs antidotes (neostigmine and atropine mixture, nalbuphine, and flumazenil) and postoperative pain management