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Fig. 4 | BMC Anesthesiology

Fig. 4

From: Nefopam downregulates autophagy and c-Jun N-terminal kinase activity in the regulation of neuropathic pain development following spinal nerve ligation

Fig. 4

The effects of nepofam on SNL-mediated autophagy and JNK activation. a Spinal cord tissue homogenates obtained from on 14 day after SNL, and analyzed for indicated proteins by Western blot analysis. β-actin was used as the loading control. Group S, sham-operated; Group C, saline-treated after SNL; Group E, nefopam-treated after SNL. b-d Densitometrical analysis for LC3-I, p62, and phospho-JNK-II. A two tailed t test was performed for comparisons between groups (n = 4). * p < 0.05, #p < 0.01

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BMC Anesthesiology

ISSN: 1471-2253

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