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Fig. 3 | BMC Anesthesiology

Fig. 3

From: Nefopam downregulates autophagy and c-Jun N-terminal kinase activity in the regulation of neuropathic pain development following spinal nerve ligation

Fig. 3

Immunohistochemical study for LC3-I/II expression in the spinal cord sections. In group S (I, IV), the immunoreactivity of LC3-I/II is visible in most cells (polygonal or ovoid) localized in the dorsal gray matter of ipsilateral spinal cord sections, which is further enhanced in group C (II, V), but suppressed in group E (III, VI). Antibody diluents, used as a negative control for LC3-I/II (VII). Group S, sham-operated; Group C, saline-treated after SNL; Group E, nefopam-treated after SNL. Original magnification, X 200

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