Table 1 Summary of the studies that examined direct effects of propofol on breast cancer cells
From: Effect of Propofol on breast Cancer cell, the immune system, and patient outcome
Study | Cell line | [Propofol] (μg/ml) | Incubation time (hr) | Proliferation (method) | Migration (method) | Invasion (method) |
|---|---|---|---|---|---|---|
Li et al | MDA-MB-231 | 2–10 | 24 |  | ↓ (wound healing) | ↓ (Matrigel membrane) |
Ecimovic et al | MDA-MB-231 | 6–10 | 24 | No change (MTT) | ↓ (8 μm pores) | No change (Matrigel membrane, 6 h) |
Ecimovic et al | MCF7 | 4–10 | 24 | No change (MTT) | ↓ (8 μm pores) | ↓ (Matrigel membrane, 6 h) |
Yu et al | a MDA-MB-435 | 2 (10 μM) | 6 | ↓ (TUNEL stain) |  |  |
Siddiqui et al | MDA-MB-231 | 20 (100 μM) | 24 | ↓ (WST-1) | No change (8 μm pores, 4 h, 5 μg/ml) |  |
Garib et al | MDA-MB-468 | 3–9 | 10 |  | ↑ (collagen matrix, video tracking) |  |
Meng et al | MDA-MB-231 | 2–10 | 12–24 | ↑ (MTT, 10 h) | ↑ (wound healing) |  |