Paravertebral dexmedetomidine as an adjuvant to ropivacaine protects against independent lung injury during one-lung ventilation: a preliminary randomized clinical trial

Table 2 Intraoperative blood gas and hemodynamics during one-lung ventilation

	C Group	R Group	Div Group	RD0.5 Group	RD1.0 Group	RD2.0 Group
P_aO₂(mmHg)
Pre	83 ± 7	86 ± 8	85 ± 8	87 ± 7	86 ± 7	86 ± 9
TLV	171 ± 24	162 ± 23	158 ± 11	168 ± 21	167 ± 17	164 ± 17
OLV₁	98 ± 13	95 ± 15	95 ± 10	100 ± 13	96 ± 9	95 ± 11
OLV₂	91 ± 8	92 ± 6	92 ± 6	92 ± 9	91 ± 7	89 ± 5
OLV₃	90 ± 6	90 ± 5	91 ± 6	90 ± 6	91 ± 6	89 ± 5
P_aCO₂(mmHg)
Pre	41 ± 3	42 ± 3	41 ± 4	40 ± 4	41 ± 3	41 ± 2
TLV	42 ± 3	42 ± 3	41 ± 4	39 ± 4	41 ± 3	40 ± 3
OLV₁	44 ± 2	45 ± 2	45 ± 3	44 ± 3	44 ± 2	45 ± 2
OLV₂	45 ± 3	45 ± 3	44 ± 3	45 ± 2	44 ± 3	44 ± 2
OLV₃	45 ± 3	45 ± 4	45 ± 4	45 ± 3	43 ± 4	44 ± 4
SpO₂(%)
Pre	96.4 ± 1.8	96.1 ± 2.1	96.9 ± 2.1	97.2 ± 1.8	97.2 ± 1.9	96.5 ± 1.9
TLV	98.8 ± 0.9	98.7 ± 1.3	98.8 ± 1.0	99.0 ± 0.8	98.7 ± 1.2	98.8 ± 0.9
OLV₁	97.2 ± 1.8	97.1 ± 2.1	98.1 ± 1.3	97.5 ± 2.0	97.9 ± 1.6	97.3 ± 1.8
OLV₂	96.4 ± 1.7	96.8 ± 2.1	96.8 ± 2.2	97.1 ± 1.9	97.3 ± 1.9	96.7 ± 2.0
OLV₃	95.9 ± 1.7	96.2 ± 2.0	96.4 ± 2.0	96.7 ± 1.8	97.0 ± 1.7	96.6 ± 2.0
MAP(mmHg)
Pre	82 ± 8	89 ± 11	84 ± 13	87 ± 12	89 ± 11	90 ± 13
TLV	86 ± 7	80 ± 8	72 ± 7^a	75 ± 7^a	72 ± 7^a	74 ± 7^a
OLV₁	86 ± 9	80 ± 11	66 ± 6^ab	68 ± 5^ab	67 ± 6^ab	68 ± 7^ab
OLV₂	71 ± 7	67 ± 6	65 ± 7	69 ± 5	65 ± 7	65 ± 8
OLV₃	68 ± 5	66 ± 5	65 ± 7	67 ± 4	63 ± 5	65 ± 7
HR(beats/min)
Pre	85 ± 6	90 ± 9	87 ± 10	89 ± 10	91 ± 11	91 ± 12
TLV	88 ± 9	90 ± 9	72 ± 9^ab	75 ± 8^ab	72 ± 8^ab	73 ± 8^ab
OLV₁	83 ± 9	75 ± 12	68 ± 6^a	71 ± 7^a	67 ± 8^a	69 ± 10^a
OLV₂	79 ± 9	72 ± 12	65 ± 6^a	68 ± 7^a	67 ± 8^a	65 ± 11^a
OLV₃	78 ± 9	71 ± 11	64 ± 6^a	67 ± 6^a	66 ± 6^a	65 ± 8^a

TLV: two-lung ventilation (immediately before initiation of OLV); OLV₁: 15 min of OLV; OLV₂: 30 min of OLV; OLV₃: immediately before the tumor tissue was excised; MAP: mean arterial pressure; HR: heart rate. Values are expressed as the mean ± SD. ^aP<0.05 vs. the C group; ^bP<0.05 vs. the R group

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