Fig. 1
From: Evaluation of small intestinal damage in a rat model of 6 Minutes cardiac arrest
Histomorphological evaluation of the jejunal wall of rats after 6 min of CA using a modified Chiu scoring system (Chiu et al. 1970) [44]. Images represent the Chiu grades 0–5. a Intact mucosa and villus structures in control tissue of sham-operated rats (Chiu grade 0). b Development of a sub-epithelial space at the tips of the villi (arrow) 24 h post-ROSC (Chiu grade 1). c Development of a Gruenhagen’s space at the tip of a villus (arrow) 24 h post-ROSC (Chiu grade 2). d Villus necrosis (arrow) 7 d post-ROSC (Chiu grade 3). e Massive epithelial desquamation and villi which are denuded of epithelial layer (arrow) 7 d post-ROSC (Chiu grade 4). f Loss of villi, mucosal ulceration and necrosis 7 d post-ROSC (Chiu grade 5). a-f Hematoxilin-eosin staining, longitudinal section of 4 μm thickness (a, e, f) or cross section (b, c, d), scale bars represent 100 μm