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Table 2 Hemodynamic parameters

From: Bispectral index to guide induction of anesthesia: a randomized controlled study

 

BIS

NON-BIS

p-value

summary statisticsa

(n = 120)

(n = 115)

 

MAP at 120 s vs. BL (%)

82 (75, 91)

83 (75, 92)

0.44

1

MAP at 240 s vs. BL (%)

71 (62, 80)

73 (65, 80)

0.23

2

MAP at 360 s vs. BL (%)

71 (64, 80)

73 (62, 84)

0.50

2

MAP at 480 s vs. BL (%)

85 (72, 98)

85 (73, 103)

0.60

0

Hypotensionb

53 (44; 35–54)

52 (45; 36–55)

0.90

0.98 (0.74–1.30)

Severe hypotensionb

12 (10; 5–17)

16 (14; 8–22)

0.42

0.72 (0.36–1.45)

Hypotension ratec

82/479 (17; 14–21)

86/460 (18; 15–23)

0.55

0.91 (0.70–1.20)

Severe hypotension ratec

17/479 (3; 2–6)

20/460 (4; 3–7)

0.22

0.82 (0.43–1.54)

Max. MAP dropd (mmHg)

33 (24, 44)

30 (21, 41)

0.26

3

 

BIS

NON-BIS

p-value

summary statisticsa

Max. MAP dropd (%)

35 (26, 43)

33 (25, 43)

0.39

2

Minimal MAP (mmHg)

61 (55, 70)

62 (54, 69)

0.98

1

Hypertensionb

0 (0; 0–2.5)

4 (3; 1–9)

0.22

0.11 (0.01–1.97)

Tachycardiab

4 (3; 1–8)

16 (14; 8–22)

0.01

0.24 (0.08–0.71)

Hypertension ratec

0/479 (0; 0–0.6)

4/460 (1; 0–2)

0.06

0.18 (0.06–1.99)

Tachycardia ratec

4/479 (1; 0–2)

18/460 (4; 2–6)

< 0.01

0.22 (0.08–0.65)

  1. Data are median (25%-, 75%-percentile) or numbers (proportion; 95% confidence interval). aData are median differences or RR and 95% CI
  2. BIS Bispectral index. MAP Mean arterial pressure. BL Baseline mean arterial pressure. bNumber of patients with that particular event at least once after administration of propofol. cProportion of this event related to all measurements following the administration of propofol, dBaseline MAP (MAP prior to administration of fentanyl) minus lowest MAP in the study period