Table 1 Patient characteristics and variables related to anesthesia and surgery

BIS

NON-BIS

p-value

(n = 120)

(n = 115)

Gender (male/female)

70/50 (58; 49-67/42; 33-51)

75/40 (65; 56-74/35; 26-44)

0.29

Age (years)

49 (35, 61)

47 (34, 61)

0.85

Height (cm)

174 (168, 180)

176 (168, 182)

0.25

Weight (kg)

78 (70, 89)

82 (71, 90)

0.14

ASA 1

42 (34; 26–43)

49 (43; 33–52)

0.26

ASA 2

65 (55; 45–63)

50 (43; 34–53)

ASA 3

13 (11; 6–18)

16 (14; 8–22)

Arterial hypertension

34 (28; 21-37)

38 (33; 25–42)

0.48

Heart failure > NYHAII

0 (0; 0–0)

3 (2.6; 1–7)

0.12

Atrial fibrillation

1 (0.8; 0–5)

2 (1.7; 0–6)

0.62

Ischemic heart disease

4 (3.3; 1–8)

7 (6.1; 2–12)

0.37

Peripheral artery disease

3 (2.5; 1–7)

0 (0; 0–0)

0.25

Diabetes

11 (9.2; 5–16)

10 (8.7; 4–15)

1.00

Dyslipidemia

6 (5; 2–11)

7 (6.1; 2–12)

0.78

β-blockers^a

16 (13; 6–18)

24 (21; 14–29)

0.16

Antihypertensive drugs^b

33 (28; 20–36)

39 (34; 25–43)

0.29

ENT surgery

103 (86; 78–92)

94 (82; 73–88)

0.65

Dermatologic surgery

13 (11; 6–18)

15 (13; 7–21)

Ophthalmic surgery

4 (3; 1–8)

6 (5; 2–11)

Tracheal tube

104 (87; 79–92)

99 (86; 78–92)

0.90

Laryngeal mask

16 (13; 8–21)

16 (14; 8–22)

Fentanyl (μg/kg)

2.7 (2.3, 2.9)

2.6 (2.3, 2.9)

0.61

Mivacurium^d

97 (81; 73–87)

93 (81; 72–88)

0.86

Rocuronium^e

8 (7; 3–13)

6 (5; 2–11)

Mivacurium (mg/kg)

0.2 (0.2, 0.3)

0.2 (0.2, 0.2)

0.67

Rocuronium (mg/kg)

0.5 (0.3, 0.5)

0.5 (0.3, 0.5)

0.90

Propofol (mg/kg)^f

1.93 (1.7, 2.3)

2 (2, 2)

0.74

Propofol airway (mg/kg)^g

2.06 (1.7, 2.4)

2 (2, 2.5)

0.07

Propofol eyelash reflex (s)^h

110 (90, 130)

110 (83, 150)

0.6

Airway (s)ⁱ

370 (320, 420)

380 (310, 430)

0.26

Failed airway^j

9 (8; 3–14)

6 (5; 2–11)

0.60

Vasopressors^k

13 (11; 6–18)

14 (12; 7–20)

0.84

Treatment of hypotension^l

17 (14; 7–19)

15 (13; 7–21)

0.85