Table 2 Multivariate analysis of the four troponin groups and different clinical outcomes (with the following covariates: age, APACHE II, sex, admission diagnosis, diabetes, chronic liver disease, chronic respiratory disease, chronic renal diseases, chronic immunosuppression, vasopressor use, sepsis, cardiac arrest, acute kidney injury, Glasgow Coma Scale, platelet, INR, bilirubin and lactic acid levels)
Variables | Group I <0.03 ng/ml N = 649 | Group II 0.03–0.3 ng/ml N = 1572 | Group III 0.3– 3 ng/ml N = 750 | Group IV >3 ng/ml N = 397 | Group II vs Group I | Group III vs Group I | Group IV vs Group I | |||
|---|---|---|---|---|---|---|---|---|---|---|
Categorical variables | aOR (95% CI) | P value | aOR(95% CI) | P value | aOR (95% CI) | P value | ||||
Hospital mortality, N (%) | 152 (23.4) | 522 (33.2) | 372 (49.6) | 228 (57.4) | 1.08 (0.84,1.38) | 0.54 | 1.64 (1.24, 2.17) | 0.0005 | 1.80 (1.30, 2.49) | 0.0004 |
Continuous renal replacement therapy, N (%) | 35 (5.4) | 179 (11.4) | 157 (20.9) | 95 (23.9) | 1.47 (0.95, 2 .26) | 0.08 | 2.12 (1.35, 3.33) | 0.001 | 1.99 (1.21, 3.27) | 0.006 |
Hemodialysis, N (%) | 24 (3.7) | 144 (9.2) | 86 (11.5) | 51 (12.9) | 1.73 (1.07, 2.79) | 0.02 | 1.92 (1.15, 3.20) | 0.01 | 1.85 (1.05, 3.26) | 0.03 |
Continuous variables | Parameter estimate (95% CI) | Parameter estimate (95% CI) | Parameter estimate (95% CI) | |||||||
ICU LOS, days Mean ± SD | 7.9 ± 9.1 | 8.8 ± 11 | 9.1 ± 10 | 8.4 ± 20.5 | 0.87 (-0.23,1.97) | 0.12 | 1.13 (-0.13, 2.40) | 0.08 | 0.48 (-1.02,1.98) | 0.53 |
Hospital LOS, days Mean ± SD | 54.8 ± 82.2 | 49.6 ± 107.4 | 40.7 ± 70.8 | 32.2 ± 182.8 | -5.23 (-15.2, 4.7) | 0.30 | -14.18 (-25.6, 2.7) | 0.02 | -22.65 (-36.2, 9.1) | 0.001 |
Mechanical ventilation duration, days, Mean ± SD | 6.1 ± 8.3 | 7.3 ± 10.1 | 8.2 ± 10.1 | 8.6 ± 9.3 | 1.15 (0.26, 2.04) | 0.011 | 2.07 (1.05, 3.09) | <0.0001 | 2.51 (1.30, 3.73) | <0.0001 |