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Fig. 1 | BMC Anesthesiology

Fig. 1

From: Repeat propofol anesthesia does not exacerbate plaque deposition or synapse loss in APP/PS1 Alzheimer’s disease mice

Fig. 1

No difference in Aβ plaque load between propofol (n = 8) and vehicle (n = 6) treated APP/PS1 mice. a An example image of Aβ plaque immunoreactivity in the cortex of an APP/PS1 mouse following repeated propofol exposure. b A representative image of Aβ plaque immunolabeling the cortex of an APP/PS1 mouse following treatment with vehicle. c Bar graph showing the percentage of the cortex occupied by Aβ plaques in propofol and vehicle treated APP/PS1 mice. d Bar graph showing the average size (μm2) of Aβ plaques in the cortex of APP/PS1 in the propofol and vehicle treatment groups. e Bar graph showing the average density of Aβ plaques (/μm2) in the cortex of propofol and vehicle exposed APP/PS1 mice. All data is shown as mean ± SEM. Scale bar = 500 μm

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