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Table 2 Proposed grading [1] adverse events [21] and estimated 30-day mortality [2]

From: Grade III bone cement implantation syndrome in malignant lung cancer patient: a case report

Grades of BCIS

Clinical findings (Donaldson)

Incidences of adverse events

Estimated 30-day mortality

Grade I

Moderate hypoxia (SPO2 < 94%) or

Hypotension [fall in systolic blood pressure (SBP) > 20%]

~ 20%

9.3%

Grade II

Severe hypoxia (SpO2 < 88%) or

Hypotension (fall in SBP > 40%) or

Unexpected loss of consciousness.

~ 3%

35%

Grade III

Cardiovascular collapse requiring Cardiopulmonary Resuscitation

~ 1%

88%