Fig. 1
From: Influence of isoflurane exposure in pregnant rats on the learning and memory of offsprings
Study protocol. The E21 pregnant rats were randomized to inhalation with isoflurane 1.3%, 2.0% or O2. After the pregnant rats gave birth, the male offspring rats were randomized to day 28 after birth (P28) and day 90 after birth (P90), followed by MWM (place navigation 5 days and spatial navigation on the 6th day). At 2 h after the spatial navigation of MWM, detect the protein expression of CREB and p-CREB in the hippocampus