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Table 2 Hemodynamic changes

From: Intravenous dexmedetomidine pre-medication reduces the required minimum alveolar concentration of sevoflurane for smooth tracheal extubation in anesthetized children: a randomized clinical trial

 

MAP (mmHg)

P value

HR (b/min)

P value

GroupD0

(n = 25)

Group D1

(n = 26)

Group D2

(n = 24)

Group D0

(n = 25)

Group D1

(n = 26)

Group D2

(n = 24)

Baseline

81 ± 7

80 ± 6

79 ± 6

0.728

108 ± 13

109 ± 12

107 ± 12

0.924

Just after pre-medicine

81 ± 7

72 ± 8*^

72 ± 6* ^

<0.000

109 ± 13

94 ± 10*^

92 ± 9*^

<0.000

Just before extubation

78 ± 7

74 ± 8*^

73 ± 7*^

<0.02

105 ± 10

99 ± 10*^

96 ± 9*^

<0.009

One min after extubation

84 ± 5#

76 ± 7^

76 ± 7^

<0.002

115 ± 13#

104 ± 9^

102 ± 9^

<0.006

Five min after extubation

82 ± 7#

76 ± 7^

76 ± 7^

<0.029

115 ± 13#

104 ± 10^

101 ± 10^

<0.008

  1. Data are expressed as mean ± standard deviation (SD) (One-way ANOVA test)
  2. MAP = arterial blood pressure, HR = heart rate
  3. Group D0 = saline group, Group D1 = dexmedetomidine group (1 μg·kg−1), Group D2 = dexmedetomidine group (2 μg·kg−1)
  4. *P < 0.05 compared with values of baseline, #P < 0.05 compared with values just before extubation, ^ P < 0.05 compared with Group D0