Perioperative Duloxetine and Etoricoxibto improve postoperative pain after lumbar Laminectomy: a randomized, double-blind, controlled study

Table 3 Pain scores (NRS) on movement in the four groups

Group Variable	Group (P) (n = 30)	Group (E) (n = 30)	Group (D) (n = 30)	Group (D/E) (n = 30)	P value
0 h	5 (5-6.25) ^d	5 (5-6) ^d	5 (5-6) ^d	5 (4.5.25) ^abc	0.013
After 2 h	5 (5-6) ^d	5 (4-6) ^d	5 (5-6) ^d	5 (4-5) ^abc	0.002
After 4 h	4 (4-5) ^d	4 (4-5) ^d	4 (4-5) ^d	4 (3-4) ^abc	0.019
After 6 h	4 (3-5) ^d	4 (3-5) ^d	4 (4-5) ^d	4 (3-4) ^abc	0.007
After 12 h	4 (3-5) ^d	4 (3-4) ^d	4 (3-4.25) ^d	3 (3-4) ^abc	0.030
After 24 h	4 (3-5) ^d	4 (3-4.25) ^d	4 (3-4) ^d	3 (2.75-4) ^abc	0.059
After 48 h	3.5 (3-4) ^d	3 (3-4) ^d	3.5 (3-4) ^d	3 (2.75-4) ^abc	0.049

Placebo group (P), Etoricoxib (E), Duloxetine (D), Duloxetine/Etoricoxib (D/E)
Data are presented as median (interquartile range). Data were analyzed by Mann–Whitney U-test and kruksal-wallis test and P < 0.05 is considered significant. a: when compared with P group
b: when compared with E group
c: when compared with D group
d: when compared with D/E group

ISSN: 1471-2253