Assessment of Haemostasis in patients undergoing emergent neurosurgery by rotational Elastometry and standard coagulation tests: a prospective observational study

Table 2 Preoperative coagulation parameters of patients undergoing emergent neurosurgery

	High Bleeders	Low Bleeders	P-value
	(N = 39)	(N = 53)	P-value
Standard coagulation tests
Platelets, 10³/mcL^a	178 (87)	194 (86)	0.403^c
Quick, %	82 (62–94)	94 (79–100)	0.018
INR, a.u.^a	1.22 (0.30)	1.07 (0.08)	0.005^c
Partial Thromboplastine Time, sec	34 (27–38)	30 (26–32)	0.383
Fibrinogen, g/L^a	2.5 (1.2)	3.1 (0.9)	0.006^c
Coagulopathy, (%)^b	19 (61.3)	13 (33.3)	0.032^d
Thromboelastometry
EXTEM
CT (s)	65 (50–88)	52 (47–62)	0.002
CFT (s)	136 (91–217)	104 (74–129)	0.001
alpha Angle	70 (60–78)	73.5 (69.5–78)	0.129
MCF (mm)	54.5 (45–63)	64 (57–69)	<0.001
INTEM
CT (s)	157 (133–180)	154 (141–167)	0.681
CFT (s)	88 (68–134)	69 (57–97)	0.005
alpha Angle	73 (64–79)	77 (74–79)	0.037
MCF (mm)	57 (50–63)	65 (57–70)	0.001
FIBTEM
MCF (mm)	12 (7–16)	16 (14–22)	<0.001
Coagulopathy, (%)^b	15 (45.6)	4 (9.3)	<0.001^d

a.u. arbitrary unit, CT coagulation time, CFT clot formation time, INR international normalized ratio, MCF maximal clot firmness
Data given as median (range) unless otherwise indicated;
^adata given as mean (standard deviation)
^bdata given as number (percentage)
Wilcoxon rank-sum test was used for statistical tests unless otherwise indicated;
^cstudent t test
^dChi-squared tests

ISSN: 1471-2253