The EC90 of remifentanil for blunting cardiovascular responses to head fixation for neurosurgery under total intravenous anesthesia with propofol and remifentanil based on bispectral index monitoring: estimation with the biased coin up-and-down sequential method

Table 1 Clinical characteristics of the 43 subjects who completed the study

Variables	Mean ± SD
Males / females (n)	20^a / 23^a
Age (y)	46.6 ± 11.0
Weight (kg)	64.1 ± 11.2
Height (cm)	163.5 ± 9.1
BMI (kg/m²)	23.9 ± 3.1
Ce of Propofol during fixation (μg/mL)	2.9 ± 0.7
BIS prior to fixation	41.2 ± 2.0
Baseline MAP (mmHg)	77.4 ± 11.7
Baseline HR (beats/min)	61.7 ± 9.8

BMI body mass index. Ce, effect-site target concentration. The results are presented as the mean ± SD or numbers^a

ISSN: 1471-2253