Fig. 3From: Levosimendan combined with epinephrine improves rescue outcomes in a rat model of lipid-based resuscitation from bupivacaine-induced cardiac arrestThe concentration of bupivacaine in cardiac tissue (a) and plasma (b). The concentration of bupivacaine in cardiac tissue in LiEL, LiE, and LiL groups were 1722 (1307, 2132) ng/g, 5115 (1811, 28,002) ng/g, 24,389 (1683, 36,474) ng/g, respectively. Significant differences were demonstrated in three groups (P = 0.002; LiEL vs. LiE, P = 0.001; LiEL vs. LiL, P = 0.007). The plasma bupivacaine concentration in LiEL, LiE, and LiL groups were (1278 ± 619) ng/mL, (6560 ± 6818) ng/mL, and 8079 ± 9614) ng/mL, respectively. They displayed differences in three groups (P = 0.011; LiEL vs. LiL, P = 0.024; LiEL vs. LiE, P = 0.013). *P < 0.05. Data were means and SD or medians and interquartileBack to article page