Fig. 4

Notch/nuclear factor κB (NF-κB) pathway was involved in the protective effect of dexmedetomidine (DMED) on oxygen-glucose deprivation (OGD)-induced neurons. a The mRNA level of Notch1. b The mRNA level of Notch intracellular domain (NICD). c The protein expressions of Notch1 and NICD. d The relative protein levels of Notch1 and NICD. e The mRNA level of NF-κB. f The mRNA level of inhibitor of NF-κB α (IκBα). g The protein expressions of NF-κB and IκBα. h The relative protein levels of NF-κB and IκBα. Data are presented as the mean ± SD. ^* p values <0.05; ^** p values <0.01; ^*** p values <0.001