Skip to main content

Table 2 Patient characteristics and perioperative clinical data in the low and high inflammatory response groups

From: Influence of the postoperative inflammatory response on cognitive decline in elderly patients undergoing on-pump cardiac surgery: a controlled, prospective observational study

 

LIR group n = 20

HIR group n = 22

Preoperative parameters

 Age (year)a

68 ± 6

69 ± 7

 Gender (n) F / Mb

9 / 11

11 / 11

 Body mass index (kg/m2)c

29.4 (24.7–33.0)

27.2 (25.4–28.8)

 Education (year)c

11 (11–12)

12 (11–12)

 BDI (score)c

9 (5.3–14.3)

8.0 (5.0–10.0)

 STAI-state (score)a

41.9 ± 10.3

41.2 ± 11.4

 EuroSCORE (%)c

3.9 (2.8–5.7)

4.3 (2.7–7.6)

 HTN (n)b

15

14

 DM (n)b

5

6

 CAD (n)b

8

9

 PVD (n)b

3

2

 COPD (n)b

3

4

 Left ventricle EF (%)c

55 (55–67)

55 (50–60)

 Creatinine (μmol/L)a

74.3 ± 12.6

84.0 ± 21.9

 Antihypertensives (n)b

15

14

 Statin use (n)b

11

5

 Antiplatelet drug (n)b

11

6

Type of surgery

 CABG (n)b

6

5

 Single valve (n)b

11

13

 Combined (n)b

3

4

Intraoperative parameters

 Aorta cross-clamp time (minute)a

67 ± 22

64 ± 20

 CPB time (minute)a

92 ± 23

91 ± 22

 Rewarming time (minute)c

18 (14–22)

17 (10–21)

 CPB temperature (°C)c

35.0 (34.7–35.4)

35.2 (34.7–35.5)

 Operation time (minute)a

193 ± 27

181 ± 41

 Bispectral indexa

44.3 ± 6.0

43.1 ± 5.6

 Propofol (mg/kg/h)a

4.1 ± 1.5

4.3 ± 1.3

 Sufentanyl (μg/kg/h)c

0.27 (0.2–0.35)

0.28 (0.21–0.3)

  1. The results are presented as the mean ± standard deviation, median (interquartile range) and number of patients
  2. aunpaired t test
  3. bχ2 test and Fischer’s exact test
  4. cMann-Whitney U test. LIR low inflammatory response, HIR high inflammatory response, F female, M male, BDI Beck Depression Inventory, STAI State-Trait Anxiety Inventory, HTN hypertension, DM diabetes mellitus, CAD coronary artery disease, PVD peripheral vascular disease, COPD chronic obstructive pulmonary disease, EF ejection fraction, CABG coronary artery bypass graft, and CPB cardiopulmonary bypass. There are no significant differences between the two groups regarding all parameters listed in this table