Table 2 Baseline characteristics of patients in each trial included in the analysis
From: The role of increased body mass index in outcomes of sepsis: a systematic review and meta-analysis
Author, year | BMI (kg/m2) categories | Sample size | Age years, mean (SD) | Male, n (%) | APACHE II, mean(SD) | SAPS II, mean (SD) | Diabetes mellitus, n (%) | Mortality data included in the analysis n (%) | Mean (SD) or median(range) | |
|---|---|---|---|---|---|---|---|---|---|---|
Hospital LOS | ICU LOS | |||||||||
Arabi [20], 2013 | underweight(<18.5) | 196 | 59.1 (19.2) | 114 (58.2%) | 25.5 (8.0) | NR | 11 (5.6) | 102 (52.0%) | 25.1 (33.6) | 9.9 (9.4) |
normal(18.5–24.9) | 1020 | 62.2 (16.8) | 630 (61.8%) | 25.7 (8.1) |  | 76 (7.5) | 451 (44.2%) | 25.1 (31.8) | 10.5 (12.5) | |
overweight(25.0–29.9) | 816 | 63.5 (15.9) | 500 (61.3%) | 25.6 (8.4) |  | 82 (10.1) | 335 (41.1%) | 27.8 (35.2) | 11.4 (14.7) | |
obese (30.0–39.9) | 680 | 62.2 (14.6) | 346 (50.9%) | 25.4 (7.9) |  | 80 (11.8) | 265 (39.0%) | 26.5 (34.8) | 11.2 (14.3) | |
morbidly obese(>40.0) | 170 | 58.4 (13.0) | 68 (40.0%) | 24.4 (7.3) | Â | 35 (20.6) | 57 (33.5%) | 34.3 (44.2) | 12.2 (12.7) | |
Chalkias [23], 2013 | normal(18.5–24.9) | 14 | NR | NR | NR | NR | NR | 2 (6.9%) | NR | NR |
overweight(25.0–29.9) | 7 |  |  |  |  |  | 0 |  |  | |
obese(30.0–39.9) | 8 |  |  |  |  |  | 3 (10.3%) |  |  | |
Gaulton [22], 2015 | underweight(<18.5) | 102 | 57.5 (19.3) | 53 (52%) | 15 (7.4) | NR | 14 (13.7%) | 24 (23.5%) | 8 (4–14) | NR |
normal(18.5–24.9) | 480 | 57 (19.3) | 271 (56.5%) | 15 (7.4) |  | 97 (20.2%) | 105 (21.9%) | 6 (4–11) |  | |
overweight(25.0–29.9) | 301 | 58 (17.0) | 189 (62.8%) | 14 (6.7) |  | 79 (26.3%) | 60 (19.9%) | 7 (4–13) |  | |
obese(30.0–39.9) | 229 | 56 (14.1) | 112 (48.9%) | 15 (5.2) |  | 81 (35.4%) | 43 (18.8%) | 6.5 (4–14) |  | |
morbidly obese(>40.0) | 79 | 50.5 (15.6) | 26 (34.2%) | 12 (7.4) |  | 23 (29.1%) | 5 (6.3%) | 5 (3–9.5) |  | |
Kuperman [21], 2013 | underweight(<18.5) | 49 | 60.3 (22.9) | 17 (34.7%) | 16.2 (6.6) | NR | 5 (10%) | 12 (24.5%) | 8.1 (7.2) | NR |
normal(18.5–24.9) | 261 | 61.2 (19.2) | 155 (59.4%) | 15.4 (5.8) |  | 44 (17%) | 46 (17.6%) | 9.3 (8.5) |  | |
overweight(25.0–29.9) | 249 | 64.2 (16.0) | 144 (57.8%) | 15.6 (5.8) |  | 52 (21%) | 40 (16.1%) | 8.8 (7.8) |  | |
obese(30.0–39.9) | 187 | 60.8 (14.2) | 102 (54.5%) | 15.9 (6.1) |  | 65 (35%) | 25 (13.4%) | 9.0 (8.1) |  | |
morbidly obese(40.0–49.9) | 46 | 60.2 (13.7) | 12 (26.1) | 14.2 (5.6) |  | 22 (48%) | 6 (13.0%) | 10.2 (9.6) |  | |
Pisitsak [24], 2016 | BMIÂ <Â 25 | 82 | NR | NR | NR | NR | NR | 22 (26.8%) | NR | NR |
BMI ≥ 25 | 175 |  |  |  |  |  | 41 (23.4%) |  |  | |
Prescott [18], 2014 | normal(18.5–24.9) | 597 | 81.3 (8.6) | 277 (46.6%) | NR | NR | 62 (10.4%) | 161 (34.0%) | NR | 10.4 (9.6) |
overweight(25.0–29.9) | 473 | 78.7 (8.6) | 274 (57.9%) |  |  | 94 (19.9%) | 96 (47.5%) |  | 11.5 (12.0) | |
obese(30.0–34.9) | 202 | 75.3 (8.1) | 93 (46.0%) |  |  | 48 (23.8%) | 36 (27.3%) |  | 11.5 (10.3) | |
Severelyobese (>35.0) | 132 | 72.8 (8.0) | 37 (28.0%) | Â | Â | 31 (23.5%) | 24 (18.2%) | Â | 12.5 (13.3) | |
Sakr [25], 2008 | underweight(<18.5) | 120 | 52.6 (21) | 55 (46.8%) | NR | 32.3 (15.8) | 6 (5%) | 23 (19.2%) | 11.8 (4.1–22.3) | 2.8 (1.4–6.4) |
normal(18.5–24.9) | 1206 | 58.4 (19.1) | 739 (61.9%) |  | 36.3 (16.8) | 75 (6.2%) | 216 (17.9%) | 12.3 (5.1–24.4) | 3.1 (1.7–7.2) | |
overweight(25.0–29.9) | 1047 | 63.6 (15) | 712 (68.8%) |  | 36.8 (17.1) | 80 (7.6%) | 181 (17.3%) | 11.1 (5.5–24.5) | 3.1 (1.7–7.0) | |
obese(30.0–39.9) | 424 | 63.5 (14.1) | 238 (56.8%) |  | 37.6 (17.7) | 34 (8%) | 84 (19.8%) | 12.2 (5.8–24.2) | 3.6 (1.8–7.1) | |
morbidly obese(>40) | 81 | 56.9 (15) | 31 (38.3%) |  | 35.7 (17.8) | 10 (12.3%) | 16 (19.8%) | 14.3 (8.4–27.4) | 4.1 (1.8–12.1) | |
Wacharasint [19], 2013 | BMIÂ <Â 25 | 276 | 63 (19.3) | 171 (62%) | 27 (8.1) | NR | 41 (14.9) | 114 (41.3%) | NR | NR |
| Â | 25Â <Â BMIÂ <Â 30 | 209 | 64 (17.0) | 142 (67.9%) | 26 (6.7) | Â | 43 (20.6) | 74 (35.4%) | Â | Â |
| Â | BMIÂ >Â 30 | 245 | 63 (14.1) | 136 (55.5%) | 27 (6.7) | Â | 73 (29.8) | 71 (29.0%) | Â | Â |