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Table 7 Rescue medication against nausea and vomiting

From: Combatting pain after orthopedic/trauma surgery- perioperative oral extended-release tapentadol vs. extended-release oxycodone/naloxone

 

Tapentadol

Oxycodone/Naloxone

  

N

Mean dose

N

Mean dose

p-value

(Chi2)

p-value

(t-test)

Metoclopramide (mg)

 Day 1

9

11

9

11

  

 Day 2

6

11

8

8

  

 Day 3

4

11

5

10

  

 Day 4

3

13

2

10

  

 Day 5

3

12

1

20

  

 Total over 5 days

15

19

21

12

0.28

0.24

Ondansetron (mg)

 Day 1

8

7

16

6

  

 Day 2

3

7

6

5

  

 Day 3

4

6

2

10

  

 Day 4

1

12

1

8

  

 Day 5

2

4

0

0

  

 Total over 5 days

12

10

19

8

0.18

0.52

Dimenhydrinate (mg)

 Day 1

1

62

1

62

  

 Day 2

0

0

0

0

  

 Day 3

0

0

0

0

  

 Day 4

0

0

0

0

  

 Day 5

0

0

0

0

  

 Total over 5 days

1

62

1

62

1.00

-

Droperidol (mg)

 Day 1

1

1.25

1

3.75

  

 Total over 5 days

1

1.25

1

3.75

0.99

-

  1. Number of patients with the respective rescue medication in mg at day x and/ or more than 1 day “Total over 5 days”