Tapentadol | Oxycodone/Naloxone | |||||
---|---|---|---|---|---|---|
N | Mean | N | Mean | p-value (Chi2) | p-value (t-test) | |
Acetaminophen (mg) | ||||||
Day 1 | 7 | 2214 | 4 | 1875 | ||
Day 2 | 8 | 3313 | 6 | 3333 | ||
Day 3 | 11 | 2727 | 6 | 3166 | ||
Day 4 | 10 | 2750 | 6 | 3667 | ||
Day 5 | 7 | 3286 | 7 | 3429 | ||
Total over 5 days | 16 | 7656 | 9 | 10278 | 0.14 | 0.32 |
Dipyrone (mg) | ||||||
Day 1 | 127 | 3484 | 124 | 3598 | ||
Day 2 | 118 | 3353 | 114 | 3338 | ||
Day 3 | 107 | 3339 | 105 | 3300 | ||
Day 4 | 99 | 3247 | 95 | 3276 | ||
Day 5 | 75 | 3127 | 80 | 3163 | ||
Total over 5 days | 130 | 13473 | 127 | 13605 | 0.31 | 0.85 |
Ibuprofen (mg) | ||||||
Day 1 | 44 | 873 | 38 | 953 | ||
Day 2 | 68 | 1515 | 66 | 1424 | ||
Day 3 | 68 | 1526 | 64 | 1469 | ||
Day 4 | 70 | 1526 | 60 | 1440 | ||
Day 5 | 67 | 1460 | 59 | 1403 | ||
Total over 5 days | 76 | 5918 | 67 | 5872 | 0.27 | 0.89 |
Etoricoxib (mg) | ||||||
Day 1 | 3 | 100 | 5 | 84 | ||
Day 2 | 3 | 90 | 5 | 84 | ||
Day 3 | 2 | 90 | 5 | 84 | ||
Day 4 | 3 | 90 | 4 | 83 | ||
Day 5 | 3 | 90 | 4 | 83 | ||
Total over 5 days | 6 | 215 | 6 | 320 | 1.00 | 0.24 |
Celecoxib (mg) | ||||||
Day 1 | 0 | 0 | 1 | 200 | ||
Day 2 | 0 | 0 | 0 | 0 | ||
Day 3 | 0 | 0 | 1 | 200 | ||
Day 4 | 0 | 0 | 1 | 200 | ||
Day 5 | 0 | 0 | 1 | 200 | ||
Total over 5 days | 0 | 0 | 2 | 400 | 0.16 | - |
Parecoxib (mg) | ||||||
Day 1 | 13 | 40 | 13 | 40 | ||
Day 2 | 0 | 0 | 0 | 0 | ||
Day 3 | 0 | 0 | 0 | 0 | ||
Day 4 | 0 | 0 | 0 | 0 | ||
Day 5 | 0 | 0 | 0 | 0 | ||
Total over 5 days | 13 | 40 | 13 | 40 | 1.00 | 1.00 |