Fig. 5

The light microscopy view of the left upper lobe lung in the S(A), IR(B), LE(C) groups, and the electron microscopy view of the left upper lobe lung in the S(D), IR(E), LE(F) groups. N, nucleus; Lb, Lamellar bodies; Mit, mitochondria. a, structure of alveoli are normal, there is no accumulation of inflammatory cells or erythrocytes observed in the alveloli. b, structure of alveoli are injured severity and widely, there were numerous inflammatory cells and erythrocytes associated with the edema and thickening in both alveolar wall and interstitial. c, microscopy examination of LE group revealed to be light damage in alveolar framework, inflammatory cells, erythrocytes and the situation of edema were alleviated visibly in LE group. d, in S group lung ultrastructural architecture was normal with type II pneumocytes containing normal Lb, no swelling of the mitochondria. e, Swelling of Lb and Mit in some type II pneumocytes were observed in group IR; Disintegrated naked nuclei and other structure of the amorphous necrotic material were observed in the alveolar cavity in IR group. f, similar incomplete and destructed of nucleus, Lb and Mit with swelling structures, but to a much lower degree than observed in LE group