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Table 3 Perioperative markers of myocardial injury and systemic inflammation

From: Comparison of the myocardial protective effect of sevoflurane versus propofol in patients undergoing heart valve replacement surgery with cardiopulmonary bypass

Marker

T0

T1

T2

T3

T4

cTnI (ng/ml)

 Propofol

0.01 (0.02)

18.26 (9.67)#

26.66 (9.10)#

13.71 (6.14)#

8.72 (4.83)#

 Sevoflurane

0.02 (0.02)

10.17 (6.63)#*

15.17 (8.73)#*

9.00 (6.43)#*

4.62 (3.40)#*

CK-MB (u/l)

 Propofol

0.87 (0.50)

47.73 (9.30)#

86.12 (7.50)#

31.79 (6.29)#

14.35 (4.31)#

 Sevoflurane

0.88 (0.60)

28.54 (7.69)#*

61.29 (8.80)#*

20.60 (7.84)#*

8.28 (2.16)#*

IL-6 (pg/ml)

 Propofol

15.86 (4.45)

36.89 (6.71)#

59.69 (7.53)#

25.80 (6.15)#

17.14 (5.17)

 Sevoflurane

13.91 (5.00)

27.87 (7.83)#*

42.67 (8.89)#*

22.64 (6.92)#

15.44 (4.54)

IL-10 (pg/ml)

 Propofol

19.07 (4.75)

56.72 (8.36)#

73.73 (7.44)#

28.35 (6.90)#

20.58 (7.56)

 Sevoflurane

16.79 (4.74)

38.24 (7.90)#*

54.29 (8.08)#*

23.70 (6.51)#

18.88 (5.50)

  1. Data are given as mean (SD). T0 = before induction, T1 = 30 min after aortic unclamping, T2 = 3 h after aortic unclamping, T3 = 24 h after surgery, T4 = 48 h after surgery. # P < 0.01 vs. T0; * P < 0.05 vs. the corresponding value in the propofol group